Sökning: "Bioinformatik och systembiologi"
Visar resultat 26 - 30 av 250 avhandlingar innehållade orden Bioinformatik och systembiologi.
26. Proteomics as a multifaceted tool in medicine and environmental assessment
Sammanfattning : Proteomics is evolving as a multi-faceted tool for addressing various biochemical and biomedical queries in the field of scientific research. This involves various stages, ranging from sample preparation to data analysis and biological interpretation. LÄS MER
27. Resistance to neuraminidase inhibitors in influenza A virus isolated from mallards
Sammanfattning : Influenza A virus belongs to the Orothomyxoviridae family of viruses and is one of the most common pathogens that cause infections of the respiratory tract. The aim of this thesis was to investigate if neuraminidase inhibitor (NAI) Tamiflu® (oseltamivir, OC) and Relenza® (zanamivir, ZA) - related resistance mutations exist in the neuraminidase (NA) gene of viruses collected from wild birds. LÄS MER
28. Characterization and Evolution of Transmembrane Proteins with Focus on G-protein coupled receptors in Pre-vertebrate Species
Sammanfattning : G protein-coupled receptors (GPCRs) are one of the largest protein families in mammals. GPCRs are instrumental for hormonal and neurotransmitter signalling and are important in all major physiological systems of the body. LÄS MER
29. On protein structure, function and modularity from an evolutionary perspective
Sammanfattning : We are compounded entities, given life by a complex molecular machinery. When studying these molecules we have to make sense of a diverse set of dynamical nanostructures with wast and intricate patterns of interactions. LÄS MER
30. From single-molecule sensing to extracellular vesicles in glioma cells under stress
Sammanfattning : This thesis describes the work I conducted in two different areas, namely biomolecular sensing and quantitative cell biology. The work in the former area was focused on the optimization of plasmonic metamaterials for sensing applications, and in the latter on the characterization of extracellular vesicles released by glioblastoma cells under stress conditions. LÄS MER