Sökning: "sequencing"

Visar resultat 1 - 5 av 970 avhandlingar innehållade ordet sequencing.

  1. 1. Sequencing cancer

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Medical Biochemistry and Biophysics

    Författare :Una Kjällquist; Karolinska Institutet.; Karolinska Institutet.; [2014]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Cancer forms highly heterogeneous tissues at several molecular levels, genomic, proteomic, transcriptomic and other epigenetic traits. The level of complexity is further augmented by the dynamic nature of tumor progression with cancer cell populations evolving in a clonal manner. LÄS MER

  2. 2. On Transcriptome Sequencing

    Detta är en avhandling från Stockholm : KTH

    Författare :Daniel Klevebring; KTH.; [2009]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transcriptome; RNA-seq; DNA sequencing; gene expression profiling; non-coding RNA; small RNA; NATURAL SCIENCES Biology Other biology Functional genomics; NATURVETENSKAP Biologi Övrig biologi Funktionsgenomik; NATURAL SCIENCES Biology Other biology Bioinformatics; NATURVETENSKAP Biologi Övrig biologi Bioinformatik; NATURAL SCIENCES Biology Cell and molecular biology Genetics; NATURVETENSKAP Biologi Cell- och molekylärbiologi Genetik; NATURAL SCIENCES Biology Cell and molecular biology Molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Molekylärbiologi; MEDICINE Morphology; cell biology; pathology Cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi;

    Sammanfattning : This thesis is about the use of massive DNA sequencing to investigate the transcriptome. During recent decades, several studies have made it clear that the transcriptome comprises a more complex set of biochemical machinery than was previously believed. LÄS MER

  3. 3. Library Preparation for High Throughput DNA Sequencing

    Detta är en avhandling från Stockholm : KTH Royal Institute of Technology

    Författare :Anders Jemt; KTH.; [2017]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; DNA; RNA; sequencing; massively parallel sequencing; library preparation; automation; genome; transcriptome; Biotechnology; Bioteknologi;

    Sammanfattning : Order 3 billion base pairs of DNA in the correct order and you get the blueprint of a human, the genome. Before the introduction of massively parallel sequencing a little more than a decade ago it would cost around $10 million to get this blueprint. LÄS MER

  4. 4. Tagging systems for sequencing large cohorts

    Detta är en avhandling från Stockholm

    Författare :Mårten Neiman; KTH.; KTH.; [2010]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; next generation sequencing; genotyping; massive parallel sequencing; 454; Pyrosequencing; amplicon sequencing; enrichment; DNA barcodes; NATURAL SCIENCES Biology Cell and molecular biology Genetics; NATURVETENSKAP Biologi Cell- och molekylärbiologi Genetik;

    Sammanfattning : Advances in sequencing technologies constantly improves the throughput andaccuracy of sequencing instruments. Together with this development comes newdemands and opportunities to fully take advantage of the massive amounts of dataproduced within a sequence run. LÄS MER

  5. 5. In situ Sequencing Methods for spatially-resolved transcriptome analysis

    Detta är en avhandling från Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Författare :Marco Mignardi; Stockholms universitet.; [2014]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Padlock probes; rolling circle amplification; in situ sequencing; spatially-resolved transcriptomics; molecular diagnostics; biokemi; Biochemistry;

    Sammanfattning : It is well known that cells in tissues display a large heterogeneity in gene expression due to differences in cell lineage origin and variation in the local environment at different sites in the tissue, a heterogeneity that is difficult to study by analyzing bulk RNA extracts from tissue. Recently, genome-wide transcriptome analysis technologies have enabled the analysis of this variation with single-cell resolution. LÄS MER