Sökning: "zanamivir"

Hittade 3 avhandlingar innehållade ordet zanamivir.

  1. 1. Prescription – Pollution – Poo – Pandemics - Priorities : Neuraminidase Inhibitors from an Environmental Resistance Development Perspective

    Författare :Marie Nykvist; Josef D. Järhult; Mikael Leijon; Uppsala universitet; []
    Nyckelord :Influenza A virus; neuraminidase inhibitor; resistance; environmental; Mallard; zanamivir; avian influenza;

    Sammanfattning : The natural Influenza A virus (IAV) host is waterfowl. Human IAV is treated with neuraminidase inhibitors (NAIs), which are stockpiled worldwide in case of an IAV pandemic. As the drugs escape regular waste water treatment, they can be detected in river waters. LÄS MER

  3. 2. Resistance to neuraminidase inhibitors in influenza A virus isolated from mallards

    Författare :Goran Orozovic; Björn Olsen; Johan Lennerstrand; Sigvard Olofsson; Linnéuniversitetet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; influenza; mallards; neuraminidase; PCR; sequencing; mutation; oseltamivir; zanamivir; resistance; NAI; antivirals; pandemic; Virology; Virologi; Molecular biology; Molekylärbiologi; Bioinformatics; Bioinformatik; Zoonotisk ekologi; Zoonotic Ecology; Virology; Virologi; Biokemi; Biochemistry;

    Sammanfattning : Influenza A virus belongs to the Orothomyxoviridae family of viruses and is one of the most common pathogens that cause infections of the respiratory tract. The aim of this thesis was to investigate if neuraminidase inhibitor (NAI) Tamiflu® (oseltamivir, OC) and Relenza® (zanamivir, ZA) - related resistance mutations exist in the neuraminidase (NA) gene of viruses collected from wild birds. LÄS MER

  4. 3. Influenza virus : protection and adaptation

    Författare :Camilla Maria Mittelholzer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Human influenza A virus; DNA vaccine; Neutralisation test; Antigen drift;

    Sammanfattning : Influenza is an acute respiratory disease caused by influenza type A and B viruses. Human influenza viruses may infect up to 15% of the total population during the seasonal epidemics, causing many cases of severe illness. Each year, approximately 350 million doses of influenza vaccine are produced for protection of those at risk of severe disease. LÄS MER