Sökning: "Robert Fredriksson"

Visar resultat 1 - 5 av 28 avhandlingar innehållade orden Robert Fredriksson.

  1. 1. Evolution and Pharmacology of Neuropeptide Y Receptors, Implications for vertebrate genome duplications

    Författare :Robert Fredriksson; Susanne Holmgren; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Evolution; tetraploidizations; G-protein coupled receptor; neuropeptide Y; zebrafish; chicken; rainbow trout; lamprey; genome duplications; peptide YY; pancreatic polypeptide; Neurovetenskap; Neurology; Neurologi; medicinsk farmakologi; Medical Pharmacology;

    Sammanfattning : The Y receptors comprise a family of evolutionarily related receptors belonging to the superfamily of G-protein coupled receptors (GPCR). Their natural ligands are in mammals neuropeptide Y (NPY), peptide YY (PYY) and pancreatic polypeptide (PP). LÄS MER

  3. 2. Digital twinning for ports : from characterization to operations’ modelling

    Författare :Robert Klar; Vangelis Angelakis; Anna Fredriksson; Anders Andersson; Niklas Arvidsson; Theo Tryfona; Statens väg- och transportforskningsinstitut; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Digital twins; Ports; Operational efficiency; Collaborative decision-making; Port decarbonization;

    Sammanfattning : Ports are actively pursuing greater operational efficiency to effectively handle the increasing global flow of goods, while striving to improve the energy efficiency of their operations to comply with new environmental regulations. As a result, innovation-leading ports have begun to recognize the potential of digital twins to overview, coordinate and optimize port processes, resulting in energy savings, and reductions of costs and of CO2 emissions. LÄS MER

  4. 3. Analysis of fluoroalkyl sulfonamide (FASA) based copolymers : An indirect source of non-polymeric PFAS

    Författare :Felicia Fredriksson; Leo W. Y. Yeung; Anna Kärrman; Ulrika Eriksson; Robert Letcher; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PFAS; FASA-based copolymers; fluorine mass balance; EOF; sludge; TF; earthworm; exposure;

    Sammanfattning : Per- and polyfluoroalkyl substances (PFAS) are an extensive group of anthropogenic compounds and are of global concern due to their negative effects on the environment and humans. Most environmental research reports non-polymeric PFAS, leading to a scarce understanding of polymeric PFAS, despite their large share on the global market. LÄS MER

  5. 4. The Gene Repertoire of G protein-coupled Receptors : New Genes, Phylogeny, and Evolution

    Författare :Þóra Kristín Bjarnadóttir; Helgi B. Schiöth; Robert Fredriksson; Kurt Kristiansen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; Bioinformatics; Evolution; GPCR; Phylogeny; Farmakologi; Pharmacological research; Farmakologisk forskning;

    Sammanfattning : The superfamily of G protein-coupled receptors (GPCRs) is one of the largest protein families of mammalian genomes and can be divided into five main families; Glutamate, Rhodopsin, Adhesion, Frizzled, and Secretin. GPCRs participate in most major physiological functions, contributing to the fact that they are important targets in drug discovery. LÄS MER

  7. 5. Characterization of Novel Solute Carriers in Humans, Mice and Flies : Solute Carriers in a Broad and Narrow Perspective

    Författare :Mikaela Ceder; Robert Fredriksson; Anita Öst; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Solute carrier; SLC; Putative SLCs; Major facilitator superfamily; MFS; Drosophila melanogaster; Glucose metabolism; UNC93A; CG4928; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : The solute carrier family is the largest family of membrane-bound transporters in humans, with 430 members divided into 65 subfamilies. They transport various substrates across lipid barriers and are vital for absorption, distribution, metabolism and excretion in all cell types in the body. LÄS MER