Sökning: "Aggregation"

Visar resultat 26 - 30 av 880 avhandlingar innehållade ordet Aggregation.

  1. 26. Arsenic-induced protein aggregation and toxicity in Saccharomyces cerevisiae

    Författare :Sansan Hua; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Arsenic; Protein aggregation; Protein quality control; Yeast;

    Sammanfattning : Arsenic is prevalent in the environment and this toxic metalloid poses a substantial threat to human health with 100-200 million people worldwide estimated to be at risk. Chronic exposure to arsenic is associated with neurodegenerative and age-related disorders that are characterized by the accumulation of protein aggregates, including Parkinson’s and Alzheimer’s disease. LÄS MER

  3. 27. Current harmonic modeling of aggregated electric vehicle loads in the low voltage grid

    Författare :Georgios Foskolos; Erik Dahlquist; Lennart Söder; Mälardalens högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Electric Vehicles; current harmonics; modeling; aggregation; power-exponential functions; Energy- and Environmental Engineering; energi- och miljöteknik;

    Sammanfattning : The proliferation of Electric Vehicles (EVs) poses new challenges for the Distribution System Operator (DSO). For example, the rectifiers that are used for charging EV batteries could significantly influence Power Quality (PQ), in terms of harmonic distortion. LÄS MER

  4. 28. Streptococci and Platelets - A Study of Host-Pathogen Interaction Dynamics

    Författare :Lisbeth Svensson; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; host-pathogen interactions; bacterial entrapment; disaggregation; aggregation; platelet activation; Streptococci;

    Sammanfattning : Invasive infections remains one of the leading causes of death due to infections over the world, and efficient treatment remains elusive. One of the major causes of sepsis and other invasive infections is pathogenic streptococci that cause a wide range of clinical manifestations in humans. LÄS MER

  5. 29. Secondary Nucleation in Amyloid Formation

    Författare :Mattias Törnquist; NanoLund: Centre for Nanoscience; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Alzheimer s disease; amyloid; Ab42; aggregation mechanism; aggregation kinetics; secondary nucleation; Protein misfolding;

    Sammanfattning : Research into Alzheimer's disease is still hampered by a lack of fundamental understanding of the underlying mechanisms. While the aggregation of the amyloid β peptide (Aβ) into amyloid fibrils is highly implicated as a key factor in the disease, the molecular nature of its involvement has proven complex and elusive. LÄS MER

  7. 30. Self-assembly of amyloid-β peptides in the presence of metal ions and interacting molecules – a detour of amyloid building blocks

    Författare :Cecilia Mörman; Astrid Gräslund; Daniel Otzen; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biophysics; Alzheimer’s disease; protein aggregation; amyloid formation; amyloid-β peptide; aggregation kinetics; interactions; metal ions; designed peptide constructs; Tau protein; NMR; circular dichroism; fluorescence spectroscopy; Biophysics; biofysik;

    Sammanfattning : Misfolding of proteins into amyloid structures is implicated as a pathological feature in several neurodegenerative diseases and the molecular causes are still unclear. One typical characteristic of Alzheimer’s disease is self-assembly and accumulation of soluble amyloid-β (Aβ) peptides into insoluble fibrils and plaques. LÄS MER