Sökning: "aggregation kinetics"

Visar resultat 1 - 5 av 52 avhandlingar innehållade orden aggregation kinetics.

  1. 1. Unravelling protein stability and aggregation

    Författare :Tanja Weiffert; NanoLund: Centre for Nanoscience; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein stability; protein aggregation; amyloid beta peptide; protein stabilization; split GFP; monellin; secretagogin; ; aggregation kinetics; toxicity; aggregation mechanism; coaggregation;

    Sammanfattning : Proteins are complex macromolecules that are fundamental to all living species. The stability of proteins are governed by non-covalent forces within the protein and between the protein and its surrounding environment. LÄS MER

  3. 2. Amyloid beta aggregation kinetics : The role of intrinsic and extrinsic factors

    Författare :Xiaoting Yang; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Alzheimer s disease; Abeta; aggregation; kinetics; secondary nucleation;

    Sammanfattning : Cerebral senile plaque is one of the main pathologies of Alzheimer's disease (AD). The amyloid cascade hypothesis suggests that the aggregation of amyloid beta (Abeta) peptide is involved in the pathogenesis of AD, which is supported by the fact that Abeta overexpression or production of more aggregation-prone variants lead to early-onset dementia. LÄS MER

  4. 3. On the molecular mechanisms of the amyloid β-peptide aggregation

    Författare :Kalyani Sanagavarapu; NanoLund: Centre for Nanoscience; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein aggregation; amyloid β-peptide; aggregation kinetics; aggregation mechanism N-terminus; mutations; variants; sequence determinants; ; cross-seeding;

    Sammanfattning : The pathogenesis of Alzheimer’s disease is widely believed to be due to production and deposition of the amyloid β-peptide. Several variants of the Aβ peptide are known to exist in in vivo. Variations include mutations or additional functional groups attached to residue side chains and may affect the aggregation process. LÄS MER

  5. 4. Towards a mechanism for surface hydrophobization of paper - Effect of combinations of polyelectrolytes and polymer particles

    Författare :Frida Iselau; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; nanoparticles; kinetics.; paper hydrophobization; starch; Surface sizing; interactions; aggregation;

    Sammanfattning : Paper materials are cost effective and light weighted, they can easily be recycled and their use as an alternative to plastics is advantageous from an environmental andsustainability perspective. However, competing with plastics for packaging applications is a challenge for cellulosic products. LÄS MER

  7. 5. Towards an understanding of surface hydrophobization of paper - Exploring the effect of polymer nanoparticles, starch, ionic strength and process parameters

    Författare :Frida Iselau; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; starch; ionic strength; paper hydrophobization; nanoparticles; penetration.; kinetics; charge ratio; temperature; aggregation; Surface sizing;

    Sammanfattning : Paper materials are cost effective and lightweight, they can easily be recycled and their use as an alternative to plastics is advantageous from an environmental and sustainability perspective. However, competing with plastics for packaging applications is a challenge for cellulosic products. LÄS MER