Sökning: "platelet activation"

Visar resultat 1 - 5 av 185 avhandlingar innehållade orden platelet activation.

  1. 1. Platelet activation and aggregation: Clinical and experimental studies

    Författare :Sukhi Singh; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :Platelet concentrate; Adrenaline; Noradrenaline; Ticagrelor; Platelet aggregation; Platelet activation;

    Sammanfattning : Background: Dual antiplatelet therapy with acetylsalicylic acid (ASA) and the adenosine diphosphate (ADP)-receptor antagonist ticagrelor increases the risk of bleeding complications during cardiac surgery. The overall aim of this thesis was to identify and evaluate current and potential methods to reduce and prevent bleeding complications in patients with ongoing antiplatelet therapy. LÄS MER

  2. 2. Platelet Adhesion to Proteins in Microplates : Applications in Experimental and Clinical Research

    Författare :Andreas Eriksson; Per Whiss; Håkan Wallén; Linköpings universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelets; platelet adhesion; platelet assay; synergistic activation; thrombosis; anti-platelet treatment; Pharmacology; Farmakologi;

    Sammanfattning : Platelets are crucial for prevention of blood loss after vessel injury. Platelet adhesion to disrupted vessel walls is mediated by receptors such as the GPIb-IX-V complex that binds von Willebrand factor and the collagen-binding integrin α2β1. LÄS MER

  3. 3. Platelet reactions in the non-self recognition of material surfaces

    Författare :Marita Broberg; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelet; biomaterial; adhesion; granule; P-selectin; plasma protein; blood; activation; release;

    Sammanfattning : Every material introduced into the body in order to function in contact with a living tissue is defined as a biomaterial. Biomaterials are used throughout the world in an increasing rate to replace and augment organ functions. The insertion of an implant into the human body will initiate blood coagulation at the surface of the material. LÄS MER

  4. 4. Platelet Activation and Inhibition in Connection with Vascular Stents

    Författare :Kjeld Christensen; Rolf Larsson; Sten Husted; Uppsala universitet; []
    Nyckelord :Medicine; platelets; inhibition; activation; stents; ACS; Medicin;

    Sammanfattning : This thesis describes the Chandler loop, which makes it possible to conduct studies in vitro of molecular and cellular interactions between whole blood and stents. It was possible to monitor activation and inhibition of the cascades systems, leukocytes and platelets by combining different platelet inhibitors and heparin coating of stents. LÄS MER

  5. 5. Platelet activation and cytokine release during experimental extracorporeal circulation

    Författare :Katrin Adrian; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :ECMO; blood-biomaterial interaction; platelets; platelet activation; cytokines; systemic inflammatory response;

    Sammanfattning : .... LÄS MER