Sökning: "circular dichroism"
Visar resultat 1 - 5 av 115 avhandlingar innehållade orden circular dichroism.
1. The circular dichroism of DNA-ligand systems
Sammanfattning : .... LÄS MER
2. Biological and Biophysical Studies on Ruthenium Complexes
Sammanfattning : Small molecules that interact with DNA through intercalation are attractive candidates for treatments against cancer and microbial infections. Octahedral ruthenium(II) polypyridyl complexes, being substitution-inert, readily synthesized and coordinately saturated, has the potential of being developed in to a new family of drugs. LÄS MER
3. Biophysical studies of membrane interacting peptides derived from viral and Prion proteins
Sammanfattning : This thesis focuses on peptides derived from the Prion, Doppel and Influenza haemagglutinin proteins in the context of bilayer interactions with model membranes and live cells. The studies involve spectroscopic techniques like fluorescence, fluorescence correlation spectroscopy (FCS), circular and linear dichroism (CD and LD), confocal fluorescence microscopy and NMR. LÄS MER
4. DNA-Complexes with Drugs and Proteins
Sammanfattning : DNA is fundamental for all living cells; the DNA holds the genetic code, which is more or less the instruction book for how all cells are built and function. Several diseases are also linked to DNA, emerging either from a mutation in our genome, which could result in a malfunctioning protein, or that the transcription of genes is somehow affected by structural changes in the DNA, induced by mutations or DNA binding molecules. LÄS MER
5. Amyloid Fibril Formation - Dye Detection and Effects of Lipids
Sammanfattning : Amyloid fibrils are long fibrillar homopolymers of self-assembled proteins. They can be formed by essentially any polypeptide, but are of particular interest because of their occurrence in several incurable and debilitating human diseases, e.g. Alzheimer’s disease (AD). LÄS MER
