Sökning: "Astrid Gräslund"

Visar resultat 1 - 5 av 24 avhandlingar innehållade orden Astrid Gräslund.

  1. 1. Radiation-induced free radicals in DNA studied by electron paramagnetic resonance

    Författare :Astrid Gräslund; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  3. 2. Modulation of Alzheimer's amyloid β peptide self-assembly : Insights into molecular mechanisms of peptide aggregation associated with Alzheimer's disease

    Författare :Axel Abelein; Astrid Gräslund; Adriaan Bax; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biophysics; biofysik;

    Sammanfattning : Misfolding of proteins and peptides is closely linked to several neurodegenerative disorders, among them Alzheimer's disease (AD), the most prominent example of brain diseases. The self-assembly of the amyloid β peptide (Aβ) into amyloid fibrils is one histologic hallmark of AD. LÄS MER

  4. 3. Modulation of amyloid β peptide self-assembly : Aggregation mechanisms associated with Alzheimer's disease

    Författare :Axel Abelein; Astrid Gräslund; Magnus Wolf-Watz; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biophysics; biofysik;

    Sammanfattning : .... LÄS MER

  5. 4. Biophysical studies of cell-penetrating peptides and of the RNR inhibitor Sml1

    Författare :Elsa Bárány-Wallje; Astrid Gräslund; Joachim Seelig; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cell-penetrating peptides; transportan; bicelles; Sml1; Biophysics; Biofysik; Biophysics; biofysik;

    Sammanfattning : Several short peptides, so called cell-penetrating peptides, have the capability to transport large hydrophilic cargos through the cell membrane. The objective is to use these peptides as drug carriers and thereby enhance the uptake of drugs into cells.Three different cell-penetrating peptides are characterized in this thesis. LÄS MER

  7. 5. Dynorphin A – Interactions with receptors and the membrane bilayer

    Författare :Johannes Björnerås; Lena Mäler; Astrid Gräslund; Göran Widmalm; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biophysics; biofysik; Biochemistry; biokemi;

    Sammanfattning : The work presented in this thesis concerns the dynorphin neuropeptides, and dynorphin A (DynA) in particular. DynA belongs to the wider class of typical opioid peptides that, together with the opioid receptors, a four-membered family of GPCR membrane proteins, form the opioid system. LÄS MER