Sökning: "telomerase activity"

Visar resultat 6 - 10 av 44 avhandlingar innehållade orden telomerase activity.

  1. 6. Integration of Molecular Biology and Morphology in Effusions with Focus on in situ Detection of Telomerase and its Components

    Författare :Nooreldin Zendehrokh; Malmö Patologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pathological anatomy; Patologi allmän ; patologisk anatomi; Diagnostics; Diagnostik; cancer; TRAP in situ; onkologi; Cytologi; cancerology; oncology; Cytology; Medicin människa och djur ; Medicine human and vertebrates ; General pathology; Telomerase;

    Sammanfattning : Clinical cytology is a rapid method to detect malignancy in effusions of the serous cavities, but the morphological characteristics of the cells do not always allow diagnosis and a specific marker for malignant cells would improve the diagnostic performance. Telomerase adds telomere repeats to the chromosome ends. LÄS MER

  3. 7. Glioblastoma multiforme in the microscope: Diagnostic features of importance for prognosis and treatment

    Författare :Annette Persson; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; General pathology; cytogenetik; Genetik; Genetics; cytogenetics; Medicin människa och djur ; macrophages; adenoviral based gene-therapy proliferation activity; telomerase activity; immunohistochemistry; Medicine human and vertebrates ; cytotoxic T-lymphocytes; diagnostic features; prognosis; immuno-therapy; Glioblastoma multiforme; neuropathology; pathological anatomy; Patologi allmän ; patologisk anatomi;

    Sammanfattning : Glioblastoma multiforme (GBM) is the most malignant and also the most common form of brain tumour in humans. The overall aim of this thesis was to investigate morphological and diagnostics features in human GBM that may be of importance for prognosis and treatment. LÄS MER

  4. 8. Studies of molecular mechanisms of telomere maintenance in Naumovozyma castellii

    Författare :Ahu Karademir Andersson; Molekylär cellbiologi; []
    Nyckelord :YEAST; Saccharomyces castellii; Naumovozyma castellii; Processvity; Telomerase; Telomere; ALT; Strain engineering;

    Sammanfattning : Telomeres are special DNA-protein structures that protect ends of chromosomes from being recognized as double-strand breaks. Telomeres consist of tandemly repeated units of TG-rich DNA and associate with telomere-specific proteins. LÄS MER

  5. 9. Predictive Factors in Esophageal Carcinoma

    Författare :Martin Dreilich; Michael Bergqvist; Anders Larsson; Daniel Brattström; Gunnar Wagenius; Claes Mercke; Uppsala universitet; []
    Nyckelord :Oncology; Esophageal carcinoma; Survival; Prognosis; Angiogenesis; HER-2; Telomerase; FMCA; HPV; Onkologi;

    Sammanfattning : Esophageal carcinoma is a malignancy with a poor prognosis and is the sixth cause of cancer related death worldwide. In Sweden approximately 400 new cases are diagnosed every year. The aim of this present thesis was to investigate predictive factors for esophageal carcinoma patients. LÄS MER

  7. 10. Telomere analysis of normal and neoplastic hematopoietic cells : studies focusing on fluorescence in situ hybridization and flow cytometry

    Författare :Magnus Hultdin; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicine; telomere; telomerase; fluorescence in situ hybridization; flow cytometry; flow-FISH; replication timing; chronic lymphocytic leukemia; immunoglobulin gene; prognosis; Biomedicin; Microbiology; Mikrobiologi; Medical Cell Biology; medicinsk cellbiologi;

    Sammanfattning : The telomeres are specialized structures at the end of the chromosomes composed of the repeated DNA sequence (TTAGGG)n and specific proteins bound to the DNA. The telomeres protect the chromosomes from degradation and end to end fusions. LÄS MER