Sökning: "FMCA"

Visar resultat 1 - 5 av 18 avhandlingar innehållade ordet FMCA.

  1. 1. Application of new methodology for preclinical development of anticancer drugs : With special focus on camptothecin derivatives and the cyanoguanidine CHS 828

    Författare :Elin Jonsson; Uppsala universitet; []
    Nyckelord :Medical sciences; drug development; hollow-fiber model; FMCA; human tumour cell; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; klinisk farmakologi; Clinical Pharmacology;

    Sammanfattning : This work describes the development and evaluation of new methods for preclinical anticancer drug development. The methods were specifically applied to study camptothecin analogues and the new compound CHS 828 (N-(4-chlorophenoxyhexyl)-N'-cyano-N"-4-pyridylguanidine) currently in early clinical trials. LÄS MER

  3. 2. Predictive Factors in Esophageal Carcinoma

    Författare :Martin Dreilich; Michael Bergqvist; Anders Larsson; Daniel Brattström; Gunnar Wagenius; Claes Mercke; Uppsala universitet; []
    Nyckelord :Oncology; Esophageal carcinoma; Survival; Prognosis; Angiogenesis; HER-2; Telomerase; FMCA; HPV; Onkologi;

    Sammanfattning : Esophageal carcinoma is a malignancy with a poor prognosis and is the sixth cause of cancer related death worldwide. In Sweden approximately 400 new cases are diagnosed every year. The aim of this present thesis was to investigate predictive factors for esophageal carcinoma patients. LÄS MER

  4. 3. The fluorometric microculture cytotoxicity assay (FMCA) in assessment of the clinical activity of cytotoxic drugs : with special reference to ovarian carcinoma

    Författare :Katalin Csóka; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  5. 4. Feasibility of the fluorometric microculture cytotoxicity assay (FMCA) in the preclinical evaluation of anticancer drugs

    Författare :Helena Fridborg; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  7. 5. In vitro analysis of cytotoxic drug activity in acute leukemia using the fluorometric microculture cytotoxicity assay (FMCA)

    Författare :Jörgen Kristensen; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER