Sökning: "Claes Mercke"

Hittade 4 avhandlingar innehållade orden Claes Mercke.

  1. 1. Radiosensitivity in lung cancer with focus on p53

    Författare :Michael Bergqvist; Claes Mercke; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Lung cancer; comet assay; p53; cDNA; p53 antibodies; Lungcancer; Komet metoden; p53 antikroppar; Onkologi; Oncology; Onkologi; Oncology; onkologi;

    Sammanfattning : In Sweden approximately 2800 new lung cancer patients are diagnosed every year. Radiotherapy is used with curative intention in certain groups of patients. The aim of this thesis is to study the basis of differences in radioresistance and the possibility to predict response to radiotherapy. LÄS MER

  2. 2. Aspects on Head and neck Cancer with special reference to Salivary Gland Tumours and Single Nucleotide Polymorphism

    Författare :Lena Cederblad; Göran Laurell; Gunilla Enblad; Erik Blomquist; Claes Mercke; Uppsala universitet; []
    Nyckelord :salivary gland carcinoma; adenoid cystic; mucoepidermoid; polymorphous low-grade carinoma; c-myc; cyclin D1; perineural;

    Sammanfattning : A thesis on Head and neck cancer focusing on dose planning, salivary gland carcinoma and Single nucleotide polymorphism.For dose planning PET/CT (Positron emissions tomography/computed tomography) with tracer gave more precise information in comparison dose planning with CT. LÄS MER

  3. 3. Predictive Factors in Esophageal Carcinoma

    Författare :Martin Dreilich; Michael Bergqvist; Anders Larsson; Daniel Brattström; Gunnar Wagenius; Claes Mercke; Uppsala universitet; []
    Nyckelord :Oncology; Esophageal carcinoma; Survival; Prognosis; Angiogenesis; HER-2; Telomerase; FMCA; HPV; Onkologi;

    Sammanfattning : Esophageal carcinoma is a malignancy with a poor prognosis and is the sixth cause of cancer related death worldwide. In Sweden approximately 400 new cases are diagnosed every year. The aim of this present thesis was to investigate predictive factors for esophageal carcinoma patients. LÄS MER

  4. 4. Oesophageal Cancer – Novel Targets for Therapy : With focus on Hsp90, EGFR, LRIG, microtubule and telomerase

    Författare :Xuping Wu; Simon Ekman; Johan Lennartsson; Ylva Pausson-Karlsson; Michael Bergqvist; Joachim Gullbo; Stefan Bergstöm; Gunilla Enblad; Claes Mercke; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hsp90; EGFR; LRIG; microtubule; telomerase; oesophageal cancer; imetelstat; DNA double-strand break; 17-AAG; radiation; prognosis; radiosensitisation; microtubule targeting agents; Oncology; Onkologi; Oncology; Onkologi;

    Sammanfattning : Oesophageal cancer is a malignant and aggressive disease with very poor survival. The aim of this thesis was to evaluate novel therapeutic targets in oesophageal cancer. In paper I, Hsp90 was expressed in all 81 oesophageal cancer tissues and also in nine oesophageal cancer cell lines. LÄS MER