Sökning: "Telomere"
Visar resultat 1 - 5 av 87 avhandlingar innehållade ordet Telomere.
1. Telomere length : dynamics and role as a biological marker in malignancy
Sammanfattning : Telomeres are protective structures at the end of our chromosomes, composed of multiple repeats of the DNA sequence TTAGGG. They are essential for maintaining chromosomal stability by preventing damage and degradation of the chromosome ends. LÄS MER
2. What modulates telomere dynamics? : Inheritance, developmental effects, and physiological challenges
Sammanfattning : Telomeres are the conservative sequence repeats located at the end of linear chromosomes that have been the focus of intensive research across many disciplines over the last four decades. They function as a cap to protect the chromosome ends from fusion to other chromosomes and to prevent chromosome degradation. LÄS MER
3. Functional Studies of Telomere-Binding Proteins in Saccharomyces castellii
Sammanfattning : Telomeres are the ends of linear eukaryotic chromosomes. The telomeres are essential for solving the end replication problem and they stabilize the genome by protection from degradation. The telomeres also protect the chromosomal ends from by being recognized as DNA breaks by the repair machinery, which could lead to end-to-end fusions. LÄS MER
4. RAP1 at the Yeast Telomere
Sammanfattning : Telomeres are specialized complexes of DNA and proteins that cap and confer stability to the ends of eukaryotic chromosomes. The telomeric DNA of most eukaryotes is composed of tandemly arranged short repeats. Within the budding yeasts these repeats are diverged in length as well as in nucleotide composition. LÄS MER
5. Exposure, telomere length, and cancer risk
Sammanfattning : Telomeres are tandem repeats of TTAGGG at the end of eukaryotic chromosomes. Telomeres play a key role in chromosome stability and regulation of the cellular lifespan. Telomeres are shortened during cell division, and probably, by not yet well characterised factors in the environment. LÄS MER