Sökning: "cytotoxic T-lymphocytes"
Visar resultat 1 - 5 av 69 avhandlingar innehållade orden cytotoxic T-lymphocytes.
1. Human intestinal T lymphocytes : a comparative analysis of phenotype and function in normal and inflamed mucosa
Sammanfattning : The epithelial lining of the gut must allow immediate contact with beneficial components as nutrients and normal microflora. At the same time it runs the constant risk of attack from pathogenic microbes and noxious agents. LÄS MER
Sammanfattning : The immune system can respond to various types of pathogens such as bacteria, viruses, tumors and parasites. The ability to provide protection against different types of pathogens partly relies on development of alternative T effector cells with separate effector functions. LÄS MER
Sammanfattning : CONTROL OF EPSTEIN-BARR VIRUS INFECTION BY CYTOTOXIC T LYMPHOCYTES Pedro-Otavio de Campos-Lima Doctoral dissertation from the Microbiology and Tumor Biology Center, Karolinska Institute, Stockholm, SwedenCytotoxic T lymphocytes (CTL) play a critical role in response to Epstein-Barrvirus (EBV), a widespread human herpesvirus that persists in healthycarriers as a latent infection of B cells and is implicated in the pathogenesisof lymphoid and epithelial cell malignancies. Six virus encoded nuclearantigens, EBNA1-6, and three membrane proteins, LMP1, -2A and -2B, areregularly detected in EBV transformed lymphoblastoid cell lines (LCLs). LÄS MER
Sammanfattning : Background: Tobacco smoking is the main cause of chronic obstructive pulmonary disease, COPD, but the mechanisms by which cigarette smoke induces COPD are still elusive. T lymphocytes have been implicated in the pathogenesis of the disease, but their role in the airway inflammation in COPD is not fully understood. LÄS MER
5. Glioblastoma multiforme in the microscope: Diagnostic features of importance for prognosis and treatment
Sammanfattning : Glioblastoma multiforme (GBM) is the most malignant and also the most common form of brain tumour in humans. The overall aim of this thesis was to investigate morphological and diagnostics features in human GBM that may be of importance for prognosis and treatment. LÄS MER