Sökning: "signaling effects"

Visar resultat 26 - 30 av 773 avhandlingar innehållade orden signaling effects.

1. 26. LRIG1 in lung cancer : prognostic effects and mechanistic studies

   Författare :Samuel Kvarnbrink; Mikael Johansson; Håkan Hedman; Odd Terje Brustugun; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lung cancer; metastasis; prognosis; LRIG1; LRIG3; LMO7; LIMCH1; Oncology; onkologi;

   Sammanfattning : Lung cancer is the leading cause of cancer-related death worldwide as well as in Sweden. Non-small cell lung cancer (NSCLC) is the predominant form, which is largely subdivided into adenocarcinomas and squamous cell carcinomas. LÄS MER

3. 27. Studies on the Swedish Parental Insurance

   Författare :Anna Amilon; Nationalekonomiska institutionen; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Nationalekonomi; ekonometri; ekonomisk teori; economic policy; satisfaction; Economics; econometrics; economic theory; economic systems; interdependence of preferences; signaling effects; cohabiting mothers; single mothers; parental leave; intra-household sharing; temporary parental leave; ekonomiska system; ekonomisk politik;

   Sammanfattning : This thesis contains an introductory chapter and three essays, all considering different aspects of the Swedish parental insurance. In the first two essays, different aspects of temporary parental leave (leave from work to take care of a sick child) are investigated, whereas the third essay considers parental leave (leave from work to take care of a new-born child). LÄS MER

4. 28. Exploring the tissue-specific nature of the Wnt cell signaling system : The complex world of cell communication and the search for the Achilles heel of cancer

   Författare :Simon Söderholm; Claudio Cantù; Mikael Benson; Stefan Hoppler; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Wnt signaling; β-catenin; Development; Cancer; Stem cells; Omics; Bioinformatics;

   Sammanfattning : The Wnt signaling pathway is a biological mechanism for cell-cell communication found across all species of the animal kingdom. This pathway plays a major role in virtually all stages of embryonic development, and it governs central aspects of stem cell biology, regeneration, and tissue homeostasis. LÄS MER

5. 29. NOTUM and RSPO3 in Bone - WNT signaling modulators regulating the skeleton

   Författare :Karin H. Nilsson; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NOTUM; RSPO3; WNT signaling; Bone;

   Sammanfattning : Osteoporosis is a skeletal disease affecting millions of people worldwide, often leading to fragility fractures and a decreased quality of life. There is an unmet medical need for new anabolic, bone building, treatments. LÄS MER

7. 30. Effects of prenatal IL-6 exposure and hyperinsulinemia on neuroendocrine regulation

   Författare :Anne-Maj Samuelsson; Göteborgs universitet; []
   Nyckelord :interleukin-6; intrauterine exposure; HPA-axis; RAS; hippocampus; spatial learning; hypertension; insulin signaling; cardiac hypertrophy;

   Sammanfattning : Prenatal exposure to infection is associated with several neuroendocrine disorders. We therefore wanted to elucidate if cytokines, generated in response to maternal infection, play a key mechanistic role in this associations. LÄS MER