Sökning: "intrauterine exposure"

Visar resultat 1 - 5 av 38 avhandlingar innehållade orden intrauterine exposure.

  1. 1. Epidemiological Studies of Preeclampsia : Maternal & Offspring Perspectives 

    Författare :Jóhanna Gunnarsdóttir; Anna-Karin Wikström; Sven Cnattingius; Ulf Högberg; Alexander Smárason; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Placental dysfunction; blood pressure; small-for-gestational-age; fetal growth restriction; intrauterine; prenatal exposure; postnatal height gain; linear growth;

    Sammanfattning : Preeclampsia is a placental-related disorder characterized by generalized endothelial activation. Vascular predisposition is associated with the occurrence of preeclampsia and the recurrence risk is substantial. LÄS MER

  3. 2. Effects of prenatal IL-6 exposure and hyperinsulinemia on neuroendocrine regulation

    Författare :Anne-Maj Samuelsson; Göteborgs universitet; []
    Nyckelord :interleukin-6; intrauterine exposure; HPA-axis; RAS; hippocampus; spatial learning; hypertension; insulin signaling; cardiac hypertrophy;

    Sammanfattning : Prenatal exposure to infection is associated with several neuroendocrine disorders. We therefore wanted to elucidate if cytokines, generated in response to maternal infection, play a key mechanistic role in this associations. LÄS MER

  4. 3. Developmental exposure to mixtures of environmental pollutants : Studies on metabolism, developmental processes, and reproductive organs in zebrafish and chicken embryos

    Författare :Anna Mentor; Maria Jönsson; Patrick Babin; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mixtures; Developmental toxicology; Endocrine disrupting chemicals; Metabolism; Feminization; Zebrafish; Chicken embryo; Biology with specialization in Environmental Toxicology; Biologi med inriktning mot miljötoxikologi; Biology with specialization in Environmental Toxicology; Biologi med inriktning mot miljötoxikologi; Biology with specialization in Environmental Toxicology; Biologi med inriktning mot miljötoxikologi; Biology with specialization in Environmental Toxicology; Biologi med inriktning mot miljötoxikologi;

    Sammanfattning : Humans and wildlife are continuously exposed to mixtures of environmental pollutants. Mixture toxicity can be challenging to predict due to interactions between chemicals and thus whole-mixture approaches are crucial in toxicology. LÄS MER

  5. 4. Transport of sodium and protons in the human placenta. Mechanisms in normal pregnancy and alterations in intrauterine growth restriction

    Författare :Martin Johansson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; placenta; Na K ATPase; Na H exchanger; H K ATPase; intrauterine growth restriction; BeWo cells; epithelial transport;

    Sammanfattning : The syncytiotrophoblast cell of the human placenta represents the interface between maternal and fetal blood supplies. This polarized epithelium consists of a maternal facing microvillous membrane (MVM) opposing a fetal facing basal membrane (BM). This unique syncytial cell is responsible for transfer of all nutrients to the developing fetus. LÄS MER

  7. 5. Exposure to birch pollen and development of atopic disease in childhood

    Författare :Anne Kihlström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Aeroallergens; atopy; infancy; sensitization; tolerance; antigen priming; intrauterine; maternal heredity; children; IgE; IgG; IgG4;

    Sammanfattning : Background: In 1993 extremely high levels of birch pollen were recorded in Stockholm, Sweden. This provided an opportunity to evaluate the effects of aeroallergen exposure on the early immune response. LÄS MER