Sökning: "signaling effects"
Visar resultat 21 - 25 av 773 avhandlingar innehållade orden signaling effects.
21. Morphological and functional effects of insulin signaling and the bHLH transcription factor Dimmed on different neuron types in Drosophila
Sammanfattning : In Drosophila, the insulin signaling pathway is at the interface between dietary conditions and control of growth and development, reproduction, stress responses and life span. Eight insulin like peptides (Dilp1-8), an insulin tyrosine kinase receptor (dInR) and its downstream components, as well as a relaxin-like receptor type (Lgr3) form the core of this signaling. LÄS MER
22. Effects of sevoflurane anesthesia on cognitive function and cholinergic signaling
Sammanfattning : In recent years, concerns have been raised regarding the potential negative impact of anesthetic drugs in postoperative cognitive dysfunction. This thesis is an attempt to contribute to the understanding of the underlying mechanisms. LÄS MER
23. Growth Hormone and Anabolic Androgenic Steroids : Effects on Neurochemistry and Cognition
Sammanfattning : Growth hormone (GH) stimulates growth and metabolism but also displays profound effects on the central nervous system (CNS). GH affects neurogenesis and neuroprotection, and has been shown to counteract drug-induced apoptosis in the brain. LÄS MER
24. The Effects of SSRI Treatment on Human Placenta and Embryo
Sammanfattning : During pregnancy, 4 - 7% of women suffer from major depressive disorder. When antidepressive treatment is needed, selective serotonin reuptake inhibitors (SSRIs) are the most commonly used. Although severe complications from SSRI treatment are rare, association with a number of adverse pregnancy and fetal outcomes has been found. LÄS MER
25. From 1p3 to PI3K - Studies of neuroblastoma
Sammanfattning : Neuroblastoma (NB) is a tumor of the sympathetic nervous system and is the most common extra-cranial tumor of childhood, accounting for 7% of all pediatric malignancies. Despite recent advances in therapeutics, outcome is still fatal for patients with aggressive NB and side-effects of treatment are severe. LÄS MER