Sökning: "transmembrane helices"
Visar resultat 1 - 5 av 32 avhandlingar innehållade orden transmembrane helices.
1. Transmembrane helices : tails, turns and snorkels
Sammanfattning : The assembly and structure of membrane proteins are intimately related. Targeting and insertion of membrane proteins into the endoplasmatic reticulum (ER) membrane involve many components that facilitate the folding of the native structure. LÄS MER
2. Marginally hydrophobic transmembrane α-helices shaping membrane protein folding
Sammanfattning : Most membrane proteins are inserted into the membrane co-translationally utilizing the translocon, which allows a sufficiently long and hydrophobic stretch of amino acids to partition into the membrane. However, X-ray structures of membrane proteins have revealed that some transmembrane helices (TMHs) are surprisingly hydrophilic. LÄS MER
3. Integration of Transmembrane Helices into the Endoplasmic Reticulum
Sammanfattning : Membrane proteins reside in cell and organelle membranes. They play significant roles in many processes vital to living cells. Receptors and ion channels are examples of membrane proteins that regulate the physiological state of the cell and are attractive targets for drug development. LÄS MER
4. Studies on the Conformation of Transmembrane Polypeptides in Membrane Proteins
Sammanfattning : The major aim of the studies that this thesis is based on has been to better define the topological determinants of the formation of so-called helical hairpins during membrane protein assembly in the ER membrane.The helical hairpin is a basic folding unit in membrane proteins. LÄS MER
5. Cotranslational protein biogenesis in Escherichia coli monitored by force profile analysis
Sammanfattning : Proteins are a diverse class of biomolecules that carry out many essential functions across all organisms. They can either be found in aqueous compartments or embedded in biological membranes of the cell and are called soluble or membrane proteins, respectively. LÄS MER