Sökning: "Mikael Benson"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden Mikael Benson.

  1. 1. Cytokines and their soluble receptors in nasal fluids from school children with allergic rhinitis

    Författare :Mikael Benson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Allergic rhinitis; school children; cytokines; soluble cytokine receptors; nasal fluids;

    Sammanfattning : Allergic inflammation is associated with a shift in the balance between cytokines produced by two T helper subsets (Th1 and Th2) towards a preponderance of Th2 cells. Interleukin (IL)-4 is produced by Th2 cells and interferon-g (IFN-g) by Th1 cells. The ratio IL-4/IFN-g is often used as a marker of the balance between the cytokines. LÄS MER

  3. 2. Creating new ventures : A longitudinal investigation of the nascent venturing process

    Författare :Mikael Samuelsson; Per Davidsson; Frédéric Delmar; Benson Honig; Jönköping University; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES;

    Sammanfattning : This study contributes, empirically, theoretically and methodologically, to entrepreneurship research, theory, and practice. I provide answers to three major questions regarding venture opportunity variation, variation in the nascent venturing process, and outcomes from this process. LÄS MER

  4. 3. Bioinformatic identification of disease associated pathways by network based analysis

    Författare :Fredrik Barrenäs; Mikael Benson; Michael Langston; Jan Komorowski; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Many common diseases are complex, meaning that they are caused by many interacting genes. This makes them difficult to study; to determine disease mechanisms, disease-associated genes must be analyzed in combination. LÄS MER

  5. 4. Identification of genes and regulators that are shared across T cell associated diseases

    Författare :Danuta R. Gawel; Mikael Benson; Mika Gustafsson; Colm Nestor; Erik Larsson Lekholm; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Genome-wide association studies (GWASs) of hundreds of diseases and millions of patients have led to the identification of genes that are associated with more than one disease. The aims of this PhD thesis were to a) identify a group of genes important in multiple diseases (shared disease genes), b) identify shared up-stream disease regulators, and c) determine how the same genes can be involved in the pathogenesis of different diseases. LÄS MER

  7. 5. Dynamic regulation of DNA methylation in human T-cell biology

    Författare :Antonio Lentini; Colm Nestor; Mikael Benson; Huan Zhang; Mika Gustafsson; Ian R. Adams; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : T helper cells play a central role in orchestrating immune responses in humans. Upon encountering a foreign antigen, T helper cells are activated followed by a differentiation process where the cells are specialised to help combating the infection. LÄS MER