Visar resultat 1 - 5 av 53 avhandlingar innehållade ordet herpesvirus.
Sammanfattning : Herpesviruses have co-speciated with several vertebrate and invertebrate animals throughout the history of evolution. In the immunocompetent human host, primary infection is usually benign, whereafter the virus is brought into life-long latency. LÄS MER
2. Herpesvirus-induced glycans: Selectin ligands and related structures on the surface of the infected cell
Sammanfattning : Human herpesviruses are usually acquired early in life and are widely distributed in the population. A common feature of all human herpesviruses is that they persist in the host after the primary infection. LÄS MER
Sammanfattning : Abstract Herpesvirus infections are common and can cause serious and life-threatening conditions in transplanted individuals. In this thesis, consisting of 4 papers (I-IV), we investigated primary infection and reactivation of Cytomegalovirus (CMV), Human Herpesvirus type 6 (HHV-6), Varicella Zoster Virus (VZV) and Epstein-Barr Virus (EBV) in transplant patients. LÄS MER
Sammanfattning : Structure biology concerns the study of the molecular structures of biological macromolecules, such as proteins, and how these relate to the function. Protein structures are also of importance in structure-based drug design. In this thesis, the work has been carried out in two different projects. LÄS MER
Sammanfattning : In order to determine and study a protein structure, large amounts of it is needed. The easiest way to obtain a protein is to recombinantly overexpress it in the well-studied bacterium Escherichia coli. However, this expression host has one major disadvantage, overexpressed proteins might not be folded or be insoluble. LÄS MER