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Visar resultat 1 - 5 av 13 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Roles of secreted bacterial factors in modulation of host cell signalling

   Författare :Eric Toh; Sun Nyunt Wai; Teresa Frisan; Staffan Bohm; Ann-Beth Jonsson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bacteria-host interaction; motility-associated killing factor A; outer membrane vesicles; cytolysin A; phosphatidylinositol 4-phosphate 5-kinase alpha; enhancer of zeste homologue 2; epigenetic modulation; Medical Cell Biology; medicinsk cellbiologi; mikrobiologi; Microbiology;

   Sammanfattning : Pathogenic bacteria employ several secretion systems to release or inject virulence factors that may alter host cell processes, generate a replicative niche, and aid bacterial survival in adverse environments. This thesis presents my investigations on how bacterial factors can modulate host cell signalling mechanisms. LÄS MER

3. 2. Non-canonical ATG8 conjugation in ESCRT-driven membrane remodeling processes

   Författare :Anastasia Knyazeva; Yao-Wen Wu; Richard Lundmark; Sascha Martens; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ATG8 conjugation; Endosomal Sorting Complex Required for Transport; membrane remodeling; chemical genetics;

   Sammanfattning : ATG8 family proteins have the unique ability to conjugate to membrane lipids. Initially identified as a hallmark of autophagy, ATG8 lipidation is emerging as an important regulator of a growing list of non-degradative cellular functions. LÄS MER

4. 3. Cognitive erosion and its implications in Alzheimer’s disease

   Författare :Selina Mårdh; Thomas Karlsson; Anders Wallin; Linköpings universitet; []
   Nyckelord :Alzheimer’s disease; longitudinal study; mixed methods design; semantic memory; awareness; metacognition; central coherence; emotions; Alzheimers sjukdom; longitudinell studie; mixed methods design; semantiskt minne; medvetande; metakognition; central koherens; emotioner; Do Psychology;

   Sammanfattning : The aim of the present thesis was twofold, first to map the semantic memory decline in Alzheimer patients over time, second to take the patient’s perspective and create a multifaceted picture of the individual with Alzheimer’s disease through the study of memory, awareness, central coherence and emotions. Further issues concerned how Alzheimer individuals handled their cognitive erosion in everyday life and if they were well calibrated with their spouse in disease related matters. LÄS MER

5. 4. Postpartum depression, depressive symptoms and parental stress in mothers and fathers 25-30 months after child birth : A family perspective

   Författare :Maude Johansson; Idor Svensson; Rolf Holmqvist; Linnéuniversitetet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Postpartum depression; Depressive symptoms; Parental stress; Child health care; Postpartum depression; Depressiva symtom; Föräldrastress; Barnhälsovården; Psychology; Psykologi;

   Sammanfattning : The overall aim of this thesis was to explore the prevalence of postpartum depression and parental stress 25 - 30 months after delivery. The first study was conducted 25 months after delivery. LÄS MER

7. 5. E-health and information- and communication technology (ICT) as support systems for older family caregivers in rural areas

   Författare :Madeleine Blusi; Mats Jong; Stefan Sävenstedt; Mittuniversitetet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; caregiver support; e-health; family caregivers; ICT; isolation; rural health; web-camera interviews; anhörigstöd; e-hälsa; informations- och kommunikationsteknologi; IKT; isolering; glesbygd; web-kamera intervjuer;

   Sammanfattning : The overall objective of the thesis was to investigate how older family caregivers in rural areas experienced participation in an e-health based caregiver support system. Participants were 95 caregivers allocated to intervention group (n=63) and control group (n=32). LÄS MER