Sökning: "Ann-Beth Jonsson"

Visar resultat 1 - 5 av 14 avhandlingar innehållade orden Ann-Beth Jonsson.

  1. 1. Host-bacteria interactions : Host cell responses and bacterial pathogenesis

    Författare :Nele de Klerk; Ann-Beth Jonsson; Teresa Frisan; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Host-bacteria interaction; Helicobacter pylori; Neisseria gonorrhoeae; Lactobacillus; Epithelial cells; Macrophages; EGR1; Amphiregulin; SabA; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Helicobacter pylori colonizes the human stomach, where it causes gastritis that may develop into peptic ulcer disease or cancer when left untreated. Neisseria gonorrhoeae colonizes the urogenital tract and causes the sexually transmitted disease gonorrhea. LÄS MER

  3. 2. Virulence Factors and Motility Mechanisms of Pathogenic Neisseria

    Författare :Jens Eriksson; Ann-Beth Jonsson; Helena Aro; Tone Tønjum; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Neisseria; Virulence factors; Type IV pili; PilT; PilU; NafA; NhhA; Twitching motility; molekylärgenetik; Molecular Genetics;

    Sammanfattning : Neisseria gonorrhoeae and Neisseria meningitidis are two closely related human specific pathogens. Neisseria gonorrhoeae is the causative agent for the sexually transmitted disease gonorrhea and often causes asymptomatic infections in women which is a cause of infertility. LÄS MER

  4. 3. Pathogenic Neisseria : Single cell motility, multicellular dynamics and antimicrobial susceptibility

    Författare :Olaspers Sara Eriksson; Ann-Beth Jonsson; Matthew Francis; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Neisseria; Type IV pili; Twitching motility; PilT; Microcolony dynamics; PilU; NafA; Antimicrobial peptide; Cell-penetrating peptide; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Neisseria meningitidis and Neisseria gonorrhoeae can colonize humans without causing any symptoms. However, gonorrhea and invasive meningococcal disease are serious health concerns. An essential virulence factor for neisserial adhesion to host cells, twitching motility and microcolony formation/aggregation is the retractile type IV pili (Tfp). LÄS MER

  5. 4. Role of lactobacilli in Helicobacter pylori pathogenesis and host cell responses

    Författare :Hanna Gebreegziabher Gebremariam; Ann-Beth Jonsson; Keira Melican; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Helicobacter pylori; Inflammation; Lactobacillus; ADAM17; Proinflammatory cytokines; Lactate; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Helicobacter pylori is well adapted to the harsh environment of the human stomach, allowing it to persistently colonize the gastric mucosa of at least 50% of the global population for decades. Long-term colonization induces chronic inflammation that can eventually lead to development of peptic ulcer and gastric cancer. LÄS MER

  7. 5. Antimicrobial peptides and virulence factors in meningococcal colonisation and disease

    Författare :Miriam Geörg; Ann-Beth Jonsson; Ole E. Sørensen; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Neisseria meningitidis; antimicrobial peptide; LL-37; cell-penetrating peptide; resistance; polynucleotide phosphorylase; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : The Gram-negative bacterium Neisseria meningitidis is a transient commensal of the human nasopharynx, but occasionally causes life-threatening disease. During colonisation of its niche, N. meningitidis has to overcome innate immune defences, including the expression of antimicrobial peptides (AMPs). LÄS MER