Visar resultat 1 - 5 av 1104 avhandlingar innehållade ordet Neurons.
Sammanfattning : Parkinson’s disease is a disorder mainly characterized by progressive degeneration of dopamine producing neurons in the substantia nigra of the midbrain. The most commonly used treatment strategy is to pharmacologically restore the lost function by the administration of the dopaminergic precursor L-DOPA. LÄS MER
Sammanfattning : Parkinson’s Disease (PD) is the most common movement disorder and second most common neurodegenerative disease. The principal hallmark of the pathology is represented by a loss of mesencephalic Dopaminergic neurons (mesDA) that reside in the Substantia Nigra pars compacta (SNpc). LÄS MER
Sammanfattning : Since the first successful derivation of human embryonic stem cells (hESC), rapid progress has been attained in the development of strategies in differentiation of these cells into various neural lineages, with the fundamental objective of using these cells for replacement and repair of damaged neuronal circuits in the central nervous system (CNS). Of particular interest are midbrain dopaminergic (mDA) neurons, which play a central role in regulation of voluntary movement. LÄS MER
Sammanfattning : The endoplasmic reticulum (ER) is crucial for protein synthesis and protein maturation, is involved in cell stress and serves in neurons as the major intracellular Ca2+ store. Neuronal ER forms a continuous network of cisterns and tubules extending from soma to a subset of dendritic spines. LÄS MER
Sammanfattning : Zinc ions are abundant in the nervous system and are involved in many biological functions. Most zinc is tightly bound to macromolecules, whereas a small fraction of zinc exists in synaptic vesicles of the zinc-enriched (ZEN) neurons, and can be visualized using various histochemical techniques, including autometallography (AMG). LÄS MER