Sökning: "enhancer of zeste homologue 2"

Hittade 2 avhandlingar innehållade orden enhancer of zeste homologue 2.

1. 1. Roles of secreted bacterial factors in modulation of host cell signalling

   Författare :Eric Toh; Sun Nyunt Wai; Teresa Frisan; Staffan Bohm; Ann-Beth Jonsson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bacteria-host interaction; motility-associated killing factor A; outer membrane vesicles; cytolysin A; phosphatidylinositol 4-phosphate 5-kinase alpha; enhancer of zeste homologue 2; epigenetic modulation; Medical Cell Biology; medicinsk cellbiologi; mikrobiologi; Microbiology;

   Sammanfattning : Pathogenic bacteria employ several secretion systems to release or inject virulence factors that may alter host cell processes, generate a replicative niche, and aid bacterial survival in adverse environments. This thesis presents my investigations on how bacterial factors can modulate host cell signalling mechanisms. LÄS MER

3. 2. Gene environment-interaction and cardiovascular phenotype in obesity and diabetes

   Författare :Shafaat Hussain; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Although a large body of evidence supports the notion that genes determine cardio-metabolic traits and outcomes, the non-genetic regulation of these events has recently gained increasing attention. Plastic chemical modifications of DNA-histone complexes defined epigenetic changes regulate gene expression by modifying chromatin accessibility to transcription factors. LÄS MER