Sökning: "interstitial fluid"

Visar resultat 21 - 25 av 64 avhandlingar innehållade orden interstitial fluid.

1. 21. Misfolded superoxide dismutase-1 in amyotrophic lateral sclerosis

   Författare :Per Zetterström; Stefan L Marklund; Lawrence J. Hayward; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ALS; SOD1; protein misfolding; SOD1 conformation; disulfide-reduced; transgenic mice; cerebrospinal fluid; protein-protein interaction; antibodies; Clinical chemistry; Klinisk kemi; Clinical Chemistry; klinisk kemi;

   Sammanfattning : Amyotrophic lateral sclerosis (ALS) is a disease in which the motor neurons die in a progressive manner, leading to paralysis and muscle wasting. ALS is always fatal, usually through respiratory failure when the disease reaches muscles needed for breathing. Most cases are sporadic, but approximately 5–10% are familial. LÄS MER

3. 22. Studies of the Biology of Intrathecal Treatment in Progressive MS

   Författare :Joakim Bergman; Anders Svenningsson; A. Tommy Bergenheim; Jonathan D. Gilthorpe; Joachim Burman; Magnus Andersson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Progressive Multiple Sclerosis; intrathecal treatment; Ommaya reservoir; anti-CD20 therapy; microdialysis; cerebrospinal fluid; CNS compartments; Progressiv Multipel Skleros; intratekal behandling; Ommaya reservoar; anti-CD20 terapi; mikrodialys; ryggmärgsvätska; sektioner i centrala nervsystemet; Neurology; neurologi;

   Sammanfattning : Background: Multiple Sclerosis (MS) is a chronic, inflammatory, autoimmune disease, affecting the central nervous system (CNS). About 85% of afflicted present with a relapsing-remitting form of the disease (RRMS), for which a breakthrough in treatment was made in 2008 with rituximab, an antibody directed towards CD20, a surface antigen on B-cells. LÄS MER

4. 23. Kidney Hyaluronan : Regulatory Aspects During Different States of Body Hydration, Nephrogenesis & Diabetes

   Författare :Louise Rügheimer; Peter Hansell; Cecilia Johnsson; Örjan Källskog; Mats Rundgren; Uppsala universitet; []
   Nyckelord :Physiology; hyaluronan; kidney; dehydration; hydration; diabetes; nephrogenesis; renomedullary interstitial cells; CD44; hyaluronan synthase; hyaluronidase; vasopressin; nitric oxide; prostaglandins; glucocorticoids; angiotensin II; diuresis; lymph vessel; podoplanin; Fysiologi;

   Sammanfattning : The kidney regulates the excretion of water and electrolytes, which maintains homeostasis and enables control of arterial blood pressure. Hyaluronan, a large negatively charged interstitial glucosaminoglycan, is heterogeneously distributed within the kidney, primarily found in the medulla. LÄS MER

5. 24. Radiation induced pneumonitis : clinical and experimental studies with special emphasis on the effect of smoking

   Författare :Kenneth Nilsson; Leif Bjerner; roger Henriksson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pneumonitis; irradiation; bronchoalveolar lavage; breast cancer; interstitial lung disease; hyaluronan; mast cell; smoking;

   Sammanfattning : Bronchoalveolar lavage (BAL) is an established method providing diagnostic support and evaluation of disease activity in interstitial lung disease (ILD). The aims of the present investigation were 1) to study the inflammatory response in pneumonitis evoked by irradiation. LÄS MER

7. 25. Transvascular fluid exchange with application to the brain. An experimental study in cat skeletal muscle and brain

   Författare :Lis Kongstad; Anestesiologi och intensivvård; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurologi; neurophysiology; neuropsychology; Neurology; intensivvård; capillary filtration coefficient; Capillary permeability; reflection coefficient; brain edema; dural puncture; Anaesthesiology; Anestesiologi; intensive care; neuropsykologi; neurofysiologi;

   Sammanfattning : This study evaluated transcapillary fluid exchange in the cat brain and in a cat skeletal muscle enclosed in a plethysmograph. A method for determination of capillary permeability (capillary filtration coefficient and reflection coefficient) and effects of transcapillary hydrostatic pressure changes were studied We found that capillary fluid permeability in a tissue can be determined by the capillary filtration coefficient, even when arterial pressure and vascular tone are changed. LÄS MER