Sökning: "Peter Hansell"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden Peter Hansell.

  1. 1. Natriuretic factors : influence on glomerular filtration, renal blood flow and electrolyte excretion in the rat

    Författare :Peter Hansell; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  3. 2. The Role of Kidney Oxygen Homeostasis for the Development of Kidney Disease

    Författare :Carla Carvalho; Fredrik Palm; Peter Hansell; Malou Friederich; Jenny Nyström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oxygen; Kidney mitochondria; Hypoxia-inducible factors; Prolyl hydroxylase; von Hippel-Lindau; Diabetes; Aging; Kidney; Sodium; RAAS; Fysiologi; Physiology;

    Sammanfattning : The relation between oxygen supply and demand determines tissue oxygen tension (PO2). When intrarenal tissue PO2 decreases, any compensatory increase in oxygen supply via increased renal blood flow is likely to increase glomerular filtration rate. LÄS MER

  4. 3. Assessment of Renal Physiology Using Functional MRI

    Författare :Per Eckerbom; Per Liss; Fredrik Palm; Peter Hansell; Jarl Jakobsen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kidney; Renal; MRI; Phase contrast; ASL; BOLD; DWI; T1; COVID-19; Radiology; Radiologi;

    Sammanfattning : Kidney injury is a major cause of morbidity and mortality throughout the world, leading to substantial individual suffering and to a heavy financial burden for the society. A large number of common conditions such as diabetes, hypertension, autoimmune diseases and infections are highly associated with kidney injury. LÄS MER

  5. 4. Diabetes-induced Alterations in Renal Microcirculation and Metabolism

    Författare :Fredrik Palm; Per Liss; Peter Hansell; Per-Ola Carlsson; Gerald DiBona; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; diabetes mellitus; kidney; nephropathy; oxygen tension; haemodynamic; nitric oxide; oxygen consumption; radical oxygen species; polyol pathway; Fysiologi; Physiology; Fysiologi;

    Sammanfattning : Diabetes-induced renal complications, i.e. diabetes nephropathy, are a major cause of morbidity and mortality. The exact mechanism mediating the negative influence of hyperglycaemia on renal function is unclear, although several hypotheses have been postulated. LÄS MER

  7. 5. Aspects of Regulation of GFR and Tubular Function in the Diabetic Kidney : Roles of Adenosine, Nitric Oxide and Oxidative Stress

    Författare :Patrik Persson; Fredrik Palm; Peter Hansell; Bengt Rippe; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetes; diabetic nephropathy; glomerular filtration rate; renal blood flow; insulin; renal hemodynamics; micropuncture; oxygen; NADPH-oxidase; apocynin; streptozotocin; l-arginine; CGS21680; rats; mice; Physiology; Fysiologi; Medical Science; Medicinsk vetenskap;

    Sammanfattning : Diabetic nephropathy is the main cause for initiation of renal replacement therapy and early symptoms in patients include increased glomerular filtration rate (GFR), decreased oxygen tension and albuminuria, followed by a progressive decline in GFR and loss of kidney function. Experimental models of diabetes display increased GFR, decreased tissue oxygenation and nitric oxide bioavailability. LÄS MER