Sökning: "brain edema"

Visar resultat 1 - 5 av 29 avhandlingar innehållade orden brain edema.

  1. 1. Pathophysiology of blood-brain barrier, brain edema and cell injury following hyperthermia : New role of heat shock protein, nitric oxide and carbon monoxide : an experimental study in rat using light and electron microscopy

    Författare :Hari Shanker Sharma; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; blood-brain barrier; heat stress; hyperthermia; brain edema; serotonin; nitric oxide; carbon monoxide; heat shock protein; glial fibrillary acidic protein; myelin basic protein; opioids; histamine; catecholamines; naloxone; indomethacin; p-CPA; electron microscopy; immunocytochemistry; Cellbiologi; Cell biology; Cellbiologi; Human Anatomy; anatomi;

    Sammanfattning : This thesis deals with the molecular mechanisms of hyperthermia induced brain damage in rats. The results clearly establish that hyperthermia caused by 4 h heat stress at 38° C is associated with a breakdown of the blood-brain barrier (BBB) permeability which seems to be instrumental in causing brain edema and cell injury. LÄS MER

  2. 2. New methodological approaches in studies on experimental brain edema : a Persoll density gradient for measurement of edema, spread of edema components in axons and DSP-4 as a tool in brain edema research

    Författare :Christer Tengvar; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  3. 3. Effects of Rho kinase, prostacyclin and L-arginine on microvascular permeability and perfusion

    Författare :Cornelia Lundblad; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fysiologi; Physiology; skeletal muscle; Rho kinase; prostacyclin; permeability; NO; experimental brain trauma; brain edema; brain contusion; microcirculation; cerebral perfusion;

    Sammanfattning : This thesis presents some effects of Rho kinase, prostacyclin (PGI2) and nitric oxide (NO) in relation to trauma and inflammation by evaluating their effects on microvascular perfusion and permeability in mouse brain and in cat skeletal muscle. PGI2 and NO are endogenous vasoactive substances produced by the endothelium. LÄS MER

  4. 4. Cerebral circulation and the sympathetic nervous system in patients with traumatic brain injury or subarachnoid hemorrhage

    Författare :Silvana Naredi; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :traumatic brain injury; brain edema; microcirculation; intracranial pressure; epo-prostenol; norepinephrine; subarachnoid hemorrhage; sympathetic nervous system; clonidine;

    Sammanfattning : Maintenance of adequate cerebral microcirculation is necessary to avoid cerebral ischemia after severe traumatic brain injury and non-traumatic subarachnoid hemorrhage. After severe traumatic brain injury the blood-brain-barrier is disrupted and transcapillary leakage will contribute to the development of vasogenic brain edema. LÄS MER

  5. 5. Transvascular fluid exchange with application to the brain. An experimental study in cat skeletal muscle and brain

    Författare :Lis Kongstad; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurologi; neurophysiology; neuropsychology; Neurology; intensivvård; capillary filtration coefficient; Capillary permeability; reflection coefficient; brain edema; dural puncture; Anaesthesiology; Anestesiologi; intensive care; neuropsykologi; neurofysiologi;

    Sammanfattning : This study evaluated transcapillary fluid exchange in the cat brain and in a cat skeletal muscle enclosed in a plethysmograph. A method for determination of capillary permeability (capillary filtration coefficient and reflection coefficient) and effects of transcapillary hydrostatic pressure changes were studied We found that capillary fluid permeability in a tissue can be determined by the capillary filtration coefficient, even when arterial pressure and vascular tone are changed. LÄS MER