Sökning: "glucose uptake rate"

Visar resultat 1 - 5 av 55 avhandlingar innehållade orden glucose uptake rate.

  1. 1. Glucose and lipid metabolism in insulin resistance an experimental study in fat cells

    Detta är en avhandling från Umeå : Folkhälsa och klinisk medicin

    Författare :Jonas Burén; Umeå universitet.; [2003]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Public health; adipocyte; insulin resistance; type 2 diabetes; insulin signalling; glucose uptake; insulin; glucose; dexamethasone; insulin receptor substrate; protein kinase B; GLUT4; lipoprotein lipase; Folkhälsomedicin; MEDICINE Social medicine Public health medicine research areas; MEDICIN Socialmedicin Folkhälsomedicinska forskningsområden; medicin; Medicine;

    Sammanfattning : Type 2 diabetes is usually caused by a combination of pancreatic β-cell failure and insulin resistance in target tissues like liver, muscle and fat. Insulin resistance is characterised by an impaired effect of insulin to reduce hepatic glucose production and to promote glucose uptake in peripheral tissues. LÄS MER

  2. 2. Impact of glucose uptake rate on recombinant protein production in Escherichia coli

    Detta är en avhandling från Stockholm : KTH Royal Institute of Technology

    Författare :Emma Bäcklund; KTH.; [2011]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; AIDA-autotransporter; Escherichia coli; fed-batch; glucose uptake rate; integral membrane proteins; outer membrane proteins; periplasmic retention; phosphotransferase system; recombinant proteins; specific growth rate; surface expression; NATURAL SCIENCES Biology; NATURVETENSKAP Biologi;

    Sammanfattning : Escherichia coli (E. coli) is an attractive host for production of recombinant proteins, since it generally provides a rapid and economical means to achieve high product quantities. LÄS MER

  3. 3. β-Adrenergic Signalling Through mTOR

    Detta är en avhandling från Stockholm : Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University

    Författare :Jessica M. Olsen; Stockholms universitet.; [2017]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glucose uptake; Brown adipose tissue; White adipose tissue; Skeletal muscle; Mechanistic target of rapamycin; Glucose transporter; Physiology; fysiologi; Physiology;

    Sammanfattning : Adrenergic signalling is part of the sympathetic nervous system and is activated upon stimulation by the catecholamines epinephrine and norepinephrine. This regulates heart rate, energy mobilization, digestion and helps to divert blood flow to important organs. LÄS MER

  4. 4. Affinity-, Partition- and Permeability Properties of the Human Red Blood Cell Membrane and Biomembrane Models, with Emphasis on the GLUT1 Glucose Transporter

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Christine Lagerquist Hägglund; Uppsala universitet.; [2003]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Affinity; Aromatic amino acids; Binding; Biomembrane; Biotin; Chromatography; Cytochalasin B; Dihydrocytochalasin B; Dissociation constant; Drug absorption; Ethanol; Equilibrium; Glucose; GLUT1; Immobilization; Immobilized biomembrane affinity chromatography; Immobilized liposome chromatography; Interaction; Liposome; Membrane protein; Membrane vesicle; Partitioning; Phospholipid bilayer; Proteoliposome; Quantitative; Red blood cell; Specific; Streptavidin; Tyrosine; Tryptophan; Biokemi; MEDICINE Chemistry Biochemistry; MEDICIN Kemi Biokemi;

    Sammanfattning : The human glucose transporter GLUT1 is abundant in red blood cells, the blood-brain barrier and epithelial cells, where it mediates the transport of the energy metabolite, glucose. In the present work some properties of GLUT1, including affinity binding of both substrates and inhibitors, transport rates as well as permeabilities of aromatic amino acids and drug-membrane interactions were analyzed by chromatographic methods. LÄS MER

  5. 5. The regulation of muscle interstitial insulin, nutrients and blood flow in insulin resistant models. An investigation using the euglycemic insulin clamp and microdialysis techniques

    Detta är en avhandling från Göteborg

    Författare :Maria Niklasson; Göteborgs universitet.; Gothenburg University.; [2000]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; insulin resistance; skeletal muscle; glucose uptake; transcapillary transport; interstitial fluid; euglycemic insulinclamp; microdialysis; blood flow; vasodilation;

    Sammanfattning : Insulin resistance, mainly located to the skeletal muscle tissue, is one prominent feature in thedevelopment of non insulin-dependent diabetes mellitus (NIDDM) and further, associated withcardiovascular diseases. In this context the importance of blood flow for insulin sensitivity has beensuggested by regulating the delivery of insulin and nutrients to the target cells. LÄS MER