Sökning: "Membrane vesicle"

Visar resultat 1 - 5 av 131 avhandlingar innehållade orden Membrane vesicle.

  1. 1. Exploring the Interplay of Lipids and Membrane Proteins

    Författare :Candan Ariöz; Åke Wieslander; Daniel O. Daley; Malcolm East; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Membrane lipids; membrane proteins; anionic lipids; membrane remodeling; intracellular vesicles; model membrane systems; glycosyltransferase; Escherichia coli; lipid composition; fatty acid modification; membrane curvature; bacterial homeoviscous adaptation; Biochemistry; biokemi;

    Sammanfattning : The interplay between lipids and membrane proteins is known to affect membrane protein topology and thus have significant effect (control) on their functions. In this PhD thesis, the influence of lipids on the membrane protein function was studied using three different membrane protein models. LÄS MER

  3. 2. Characterization of artificial and biological lipid vesicles using TIRF and SPR

    Författare :Thomas Olsson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; membrane permeability; chromaffin vesicle; fluorescence; total internal reflection TIRF microscopy; surface plasmon resonance SPR ; vesicle; osmotic shock; cell membrane; liposome; nanoparticle tracking analysis NTA ; large dense core vesicles LDCVs ;

    Sammanfattning : Synthetic lipid vesicles serve as important mimics of cells and the natural membranes that they are enclosed by. As such they are frequently used as simplified models of the highly complex cell membrane to aid in-depth physicochemical and biological characterization of this essential biological structure. LÄS MER

  4. 3. Interaction of Calcium Ions with Lipid Membranes

    Författare :Baharan Ali Doosti; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; phospholipid bilayer membrane; membrane dynamics; micromanipulation; calcium ions; cell migration.; membrane nanotube; membrane tubular protrusions; calcium ion concentration gradient; membrane bending; giant unilamellar vesicle;

    Sammanfattning : Bilayer membranes enclose and shield the biological cell and its inner compartments, as well as the tubular networks that exist within and between the cells. Due to their fluidic nature, the membranes are incredibly dynamic and flexible, which allows them to bend, reshape and fuse in response to mechanical and chemical stimuli within their natural microenvironments. LÄS MER

  5. 4. Membrane-bound proteins : Characterization, evolution, and functional analysis

    Författare :Misty M. Attwood; Helgi B. Schiöth; Arne Elofsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transmembrane protein; alpha-helical membrane protein; evolution membrane proteins; 3TM; 4TM; 5TM; trispanin; Bioinformatics; Bioinformatik;

    Sammanfattning : Alpha-helical transmembrane proteins are important components of many essential cell processes including signal transduction, transport of molecules across membranes, protein and membrane trafficking, and structural and adhesion activities, amongst others. Their involvement in critical networks makes them the focus of interest in investigating disease pathways, as candidate drug targets, and in evolutionary analyses to identify homologous protein families and possible functional activities. LÄS MER

  7. 5. Membrane-mimetic systems : Novel methods and results from studies of respiratory enzymes

    Författare :Gustav Nordlund; Peter Brzezinski; Joachim Heberle; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Lipids; membrane proteins; method development; respiration; reconstitution; supported membranes; SNAREs; liposome fusion; lipid-protein interactions; Biochemistry; biokemi;

    Sammanfattning : The processes localized to biological membranes are of great interest, both from a scientific and pharmaceutical point of view. Understanding aspects such as the detailed mechanism and regulation of these processes requires investigation of the structure and function of the membrane-bound proteins in which they take place. LÄS MER