Sökning: "glucose uptake rate"

Visar resultat 11 - 15 av 60 avhandlingar innehållade orden glucose uptake rate.

  1. 11. Regulation of glucose transport and insulin-stimulated GLUT4 translocation in skeletal muscle

    Författare :Jorge E Rincón Viatela; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :skeletal muscle; glucose transport; insulin resistance; hyperglycaemia; steroid hormones; smoking; nicotine;

    Sammanfattning : Skeletal muscle represents about 40% of body mass and accounts for at least 80% of glucose disposal under insulin-stimulated conditions. Furthermore, GLUT4 transport protein is the primary component of the glucose transport system in skeletal muscle. LÄS MER

  3. 12. Insulin signaling and glucose transport in insulin resistant human skeletal muscle

    Författare :Håkan K R Karlsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Skeletal muscle; insulin resistance; type 2 diabetes; glucose transport; insulin signaling; first-degree relatives; AS160; SelS; rosiglitazone treatment;

    Sammanfattning : Insulin resistance in skeletal muscle is a hallmark feature of Type 2 diabetes mellitus. The overall aim of this thesis was to investigate downstream intermediates in the insulin signaling pathway in an attempt to characterize the molecular mechanism of skeletal muscle insulin resistance in Type 2 diabetes. LÄS MER

  4. 13. Roles of PI3-kinase and ARAP2 in regulating glucose metabolism

    Författare :Aditi Chaudhari; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PI3-kinase; Type 2 diabetes; ARAP2; Lipid droplets; metabolism;

    Sammanfattning : Insulin signaling is mediated by a complex, highly integrated network which functions to control multiple metabolic and growth processes throughout the organism. A key enzyme in the insulin signaling network is phosphatidylinositol 3-kinase (PI3-kinase). LÄS MER

  5. 14. The temperature-limited fed-batch technique for control of Escherichia coli cultures

    Författare :Marie Svensson; Sven-Olof Enfors; John Villadsen; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Endotoxin; Escherichia coli; fed-batch technique; glucose-limitation; mathematical model; Bioengineering; Bioteknik;

    Sammanfattning : The objective of this study was to investigate the physiology and productivity in Escherichia colicultures with emphasis on the temperature-limited fed-batch (TLFB) culture. The TLFB techniquecontrols the oxygen consumption rate of the growing culture by a gradually declining temperaturefrom 37-35 °C down to 20-18 °C. LÄS MER

  7. 15. Regulation of whole-body glucose and lipid metabolism by skeletal muscle

    Författare :Milena Schönke; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Obesity and associated diseases like type 2 diabetes are rapidly growing health concerns across the globe. The uptake and expenditure of energy in the body are tightly regulated by a plethora of enzymes and hormones in central and peripheral tissues. LÄS MER