Sökning: "in vitro evolution"

Visar resultat 1 - 5 av 79 avhandlingar innehållade orden in vitro evolution.

  1. 1. Protein–DNA Recognition In Vitro Evolution and Characterization of DNA-Binding Proteins

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Mikael Nilsson; Uppsala universitet.; [2004]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; In vitro evolution; Phage display; mRNA display; Cro; DNA recognition; repressor; Biokemi; NATURAL SCIENCES Chemistry Biochemistry; NATURVETENSKAP Kemi Biokemi;

    Sammanfattning : DNA-recognizing proteins are involved in a multitude of important life-processes. Therefore, it is of great interest to understand the underlying mechanisms that set the rules for sequence specific protein–DNA interactions. Previous attempts aiming to resolve these interactions have been focused on naturally occurring systems. LÄS MER

  3. 2. Molecular Evolution of Neuropeptide Y Receptors in Vertebrates

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Erik Salaneck; Uppsala universitet.; [2001]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Neuropeptide Y; Receptor; Evolution; Neurovetenskap; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Neurology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Neurologi; Neurology; neurologi;

    Sammanfattning : The three evolutionarily related peptides neuropeptide Y (NPY), peptide YY (PYY) and pancreatic polypeptide (PP) are ligands to at least five G-protein coupled receptors in mammals, which are denoted by numbers. NPY has many physiological effects including stimulation of appetite and regulation of circadian rhythm and blood pressure. LÄS MER

  4. 3. In vivo and in vitro evolution of molecular mechanisms - Importance in B cell development and phage display

    Detta är en avhandling från Department of Immunotechnology, Lund University

    Författare :Nina Nilsson; Lunds universitet.; Lund University.; [2000]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; B cell development and phage display; transplantation; serology; Immunology; Immunologi; serologi; Biology; Biologi;

    Sammanfattning : Bone marrow resident hematopoietic stem cells differentiate into all different types of lymphoid populations, there among mature naive B cells expressing IgM and IgD. During the maturation, the B cells are subjected to several steps of selection to ensure proper development of the antigen receptor. LÄS MER

  5. 4. Evolution of olfaction in Lepidoptera and Trichoptera : Gene families and antennal morphology

    Detta är en avhandling från Lund University, Faculty of Science, Department of Biology

    Författare :Jothi Kumar Yuvaraj; Lunds universitet.; Lund University.; [2017-10]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; evolution; pheromone receptors; olfaction; chemosensory; sensillum; HEK 293 cells;

    Sammanfattning : Resultaten i denna avhandling ökar vår kunskap om hur evolutionen av feromondetektering hos fjärilar gått till.Luktsinnet är viktigt för de flesta djur, inklusive människor, hundar, insekter och många andra. LÄS MER

  7. 5. Biochemical Studies on a Plant Epoxide Hydrolase Discovery of a Proton Entry and Exit Pathway and the Use of In vitro Evolution to Shift Enantioselectivity

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Ann Gurell; Uppsala universitet.; [2010]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; epoxide hydrolase; enantioselectivity; in vitro evolution; proton wire; epoxides; selectivity; CASTing; structure-function; NATURAL SCIENCES Chemistry Biochemistry; NATURVETENSKAP Kemi Biokemi; Biokemi; Biochemistry;

    Sammanfattning : The work leading to this thesis has provided additional information and novel knowledge concerning structure-function relationship in the potato epoxide hydrolase.Epoxide hydrolases are enzymes catalyzing the hydrolysis of epoxides to yield the corresponding vicinal diols. LÄS MER