Sökning: "GLUT4"
Visar resultat 1 - 5 av 35 avhandlingar innehållade ordet GLUT4.
1. Glucose and lipid metabolism in insulin resistance : an experimental study in fat cells
Sammanfattning : Type 2 diabetes is usually caused by a combination of pancreatic β-cell failure and insulin resistance in target tissues like liver, muscle and fat. Insulin resistance is characterised by an impaired effect of insulin to reduce hepatic glucose production and to promote glucose uptake in peripheral tissues. LÄS MER
2. Targeting Nutrient Transporters in Acute Myeloid Leukemia
Sammanfattning : .... LÄS MER
3. Regulation of glucose transport and insulin-stimulated GLUT4 translocation in skeletal muscle
Sammanfattning : Skeletal muscle represents about 40% of body mass and accounts for at least 80% of glucose disposal under insulin-stimulated conditions. Furthermore, GLUT4 transport protein is the primary component of the glucose transport system in skeletal muscle. LÄS MER
4. Mechanisms regulating metabolic and mitogenic events in skeletal muscle : implications for insulin resistance and exercise
Sammanfattning : Reduced glucose transport in skeletal muscle is a hallmark feature of Type II diabetes. Numerous mechanisms acutely or chronically regulate skeletal muscle glucose transport. The role of GLUT4, mitogen-activated protein kinases (MAPK), and peroxisome proliferator-activated receptor [gamma] (PPAR[gamma]) were examined in skeletal muscle. LÄS MER
5. Gene regulation, intracellular signaling and membrane traffic : studies in primary human skeletal muscle cultures
Sammanfattning : Skeletal muscle is an insulin sensitive organ and plays a major role in whole body electrolyte and substrate homeostasis in the post prandial state. Impaired insulin action in skeletal muscle may lead to the pathological condition of insulin resistance. LÄS MER