Sökning: "bröstcancer"

Visar resultat 26 - 30 av 177 avhandlingar innehållade ordet bröstcancer.

1. 26. Radiotherapy in Early Breast Cancer

   Författare :Fredrika Killander; Bröstcancer-genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pentoxifylline; cyclophosphamide; tamoxifen; side effects; randomised trial; Breast cancer; radiotherapy;

   Sammanfattning : Radiotherapy (RT) after mastectomy has been part of the treatment for early breast cancer since the 1940s. The treatment reduces the risk of loco-regional recurrences, but implies risk of late side effects that can begin decades after RT. LÄS MER

3. 27. Wnt-5a Signalling in Human Mammary Cells: Implications for the Development of Breast Cancer

   Författare :Marzieh Jönsson; Bröstcancer-genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; Cytology; signalling; breast cancer; Wnt-5a; mammary epithelial cells; cancer; onkologi; Cytologi; cancerology;

   Sammanfattning : The Wnt-5a gene encodes a secreted protein that regulates several normal processes in embryonic and adult tissues by as yet unknown mechanisms. Expression of Wnt-5a protein does not cause cell transformation, but it instead counteracts the effects induced by transforming Wnts. LÄS MER

4. 28. On the Role of Polyamines in Apoptosis

   Författare :Cecilia Hegardt; Bröstcancer-genetik; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; SSAT; DENSPM; spermine; polyamines; mitochondrial membrane potential; cytochrome c; caspase; flow cytometry; Jurkat cells; mouse thymocytes; thymus in vivo; programmed cell death; Dexamethasone-induced apoptosis; Fas-induced apoptosis; AdoMetDC; Cytology; oncology; cancerology; Cytologi; onkologi; cancer; Clinical biology; Klinisk biologi; Animal physiology; Djurfysiologi;

   Sammanfattning : Apoptosis is a kind of death that is best described as cellular suicide and it is important for normal tissue homeostasis. The process can be induced by a number of different stimuli and the dying cell goes through a defined pathway terminating in typical biochemical and morphological alterations of the cell. LÄS MER

5. 29. Molecular Genetic Alterations In Endometrial And Ovarian Cancers

   Författare :Anjila Koul; Bröstcancer-genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; KRAS; PTEN; TP53; Overexpression; Mutation; Microsatellite instability; Complex atypical hyperplasia; Endometrial cancer; Ovarian cancer; cancer; onkologi; Cytologi; cancerology; oncology; Cytology; CNS metastasis; Cytogenetic analysis; BRCA2; BRCA1; B-catenin; CDKN2A;

   Sammanfattning : Endometrial cancer is the most common gynecological cancer diagnosed in western countries. Complex atypical hyperplasia (CAH) reflects a state of hyperestrinism and its role as a precursor lesion of this cancer is established. LÄS MER

7. 30. Epigenetic and Phenotypic Profiling of Urothelial Carcinoma

   Författare :Mattias Aine; Bröstcancer-genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epigenetics; DNA methylation; gene expression; urothelial carcinoma; bladder cancer;

   Sammanfattning : Precise spatial and temporal regulation of gene expression programs is a prerequisite for multicellular life. Since the discovery of DNA as the carrier of genetic information, a key question in biology has been how these hard coded instructions are read and regulated to maintain cellular and organismal homeostasis. LÄS MER