Sökning: "caspase"
Visar resultat 1 - 5 av 267 avhandlingar innehållade ordet caspase.
1. Caspase-dependent and caspase-independent neuronal injury in the developing brain
Sammanfattning : Aims: To investigate the mechanisms of neuronal cell death after hypoxia-ischemia in the developing brain.Methods: Rats or mice were subjected to left common carotid artery ligation plus hypoxia. Animals were sacrificed at certain time points after hypoxia-ischemia. LÄS MER
2. Caspase activation in human neuroblastoma cells: mechanisms and spatiotemporal aspects
Sammanfattning : Apoptosis is one of the modes of programmed cell death, in which several members of the caspase family of proteases play the central role. However, activation of apoptotic caspases does not necessarily lead to cell death. LÄS MER
3. The role of caspase-1, caspase-4, NLRP3 and IL-1RA in bladder epithelial cells infected by uropathogenic Escherichia coli
Sammanfattning : Urinary tract infection is one of the most common infections and is mostlycaused by uropathogenic Escherichia coli (UPEC). The inflammasomeassociatedproteins caspase-1, caspase-4 and NLRP3 are essential in the hostcell response during urinary tract infection by regulating IL-1β release. LÄS MER
4. Caspase-3 in lens epithelium
Sammanfattning : Purpose: To model the time evolution of active caspase-3 protein expression in a healthy lens, and in a lens exposed to UVR-300 nm (UVR-B). To develop an automated method to classify the fluorescent signal of biomarkers in the lens epithelial cells.Methods: Six-week old Sprague-Dawley rats were used. LÄS MER
5. Amyotrophic Lateral Sclerosis – A Study in Transgenic Mice
Sammanfattning : Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with an incidence of 1.5-2.7/100000 people/year. Today there is no cure for the disease and only symptomatic treatments are available. LÄS MER