Sökning: "mammary epithelial cells"

Visar resultat 1 - 5 av 47 avhandlingar innehållade orden mammary epithelial cells.

  1. 1. Estrogen receptor signalling in mammary epithelial cells

    Författare :Malin Hedengran Faulds; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :ER; STAT5; mammary epithelial cell differentiation; EGF; DAX-1;

    Sammanfattning : The mammary gland is a complex tissue going through cycles of extensive proliferation and differentiation. Many hormones are involved in the regulation of development of the mammary gland, including estrogen, prolactin and epidermal growth factor (EGF). LÄS MER

  3. 2. STAT5 expression and regulation in mammary epithelial cells

    Författare :Hanne Olsen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :STAT5; JAK2; PPAR-gamma; ER; MAPK; mammary epithelial cell differentiation;

    Sammanfattning : The mammary gland of an adult mammal undergoes cycles of proliferation and differentiation influenced by growth factors, peptide, and steroid hormones, e.g. epidermal growth factor (EGF), prolactin (PRL) and estrogen (E). LÄS MER

  4. 3. Wnt-5a Signalling in Human Mammary Cells: Implications for the Development of Breast Cancer

    Författare :Marzieh Jönsson; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; Cytology; signalling; breast cancer; Wnt-5a; mammary epithelial cells; cancer; onkologi; Cytologi; cancerology;

    Sammanfattning : The Wnt-5a gene encodes a secreted protein that regulates several normal processes in embryonic and adult tissues by as yet unknown mechanisms. Expression of Wnt-5a protein does not cause cell transformation, but it instead counteracts the effects induced by transforming Wnts. LÄS MER

  5. 4. Estrogen receptor β signalling in mammary epithelial and breast cancer cells

    Författare :Karolina Lindberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Estrogens are key players in the etiology and progression of breast cancer, and mediate their effects through the estrogen receptors (ERα and ERβ). ERα plays important roles in proliferation and progression of breast cancer, whereas a distinct function of ERβ in the initiation and development of breast cancer is not yet clearly established. LÄS MER

  7. 5. Effects of c-erbB2 signaling on morphogenesis and cell adhesion in mammary epithelial cells

    Författare :Lachmi E Jenndahl; Göteborgs universitet; []
    Nyckelord :e-erbB2; integrin alpha2beta1; integrin regulation; ILK; PKB; Rho; epithelial-mesenchymal transition EMT ; E-cadherin; Anchorage independent growth AIG ;

    Sammanfattning : .... LÄS MER