Sökning: "Serum"

Visar resultat 21 - 25 av 2031 avhandlingar innehållade ordet Serum.

  1. 21. Fat cell insulin resistance : an experimental study focusing on molecular mechanisms in type 2 diabetes

    Författare :Frida Renström; Jan Eriksson; Anna Krook; Umeå universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; adipocyte; insulin signaling; insulin; glucose; IRS-1; glucose uptake; insulin resistance; typ 2 diabetes; serum; Medicine; Medicin;

    Sammanfattning : The aim of the present thesis was to further increase our understanding of mechanisms contributing to and maintaining cellular insulin resistance in type 2 diabetes (T2D). For this reason, the effects of high glucose and insulin levels on glucose transport capacity and insulin signaling, with emphasis on insulin receptor substrate 1 (IRS-1) were assessed in fat cells. LÄS MER

  3. 22. Estimating children’s exposure to per- and polyfluoroalkyl substances

    Författare :Kerstin Winkens; Ian T. Cousins; Urs Berger; Robin Vestergren; Heather M. Stapleton; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PFAS; PFAA; fluorinated; fluorotelomer; FTOH; PAP; early life; child; human; exposure; intake; indoor; bedroom; air; dust; serum; Applied Environmental Science; tillämpad miljövetenskap;

    Sammanfattning : Per- and polyfluoroalkyl substances (PFASs) are highly stable, surface active chemicals, which are water- and oil/stain-repellent. Because of their unique properties, PFASs are widely used in consumer products. LÄS MER

  4. 23. Polyunsaturated fatty acids and allergy development

    Författare :Sara Johansson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DTH; IgE; fish oil; farming; atopy; butter; allergy; saturated fat; fatty acids; polyunsaturated fatty acids; breast milk; margarine; serum; cord blood;

    Sammanfattning : Allergies have increased strikingly in the affluent parts of the world during the last century. The cause of the rapid increase is unknown but several risk factors have been postulated, the main ones relating to reduced microbial exposures and changed diet. LÄS MER

  5. 24. EMBRYONIC GLIA AND FOREBRAIN NEUROGENESIS; in vitro generation and differentiation of telencephalic neurons

    Författare :Charlotta Skogh; Neurobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; beta tubulin III; GFAP; RC2; Neurology; neuropsychology; neurofysiologi; DARPP-32; retinoic acid; serum; EGF; co-culture; cell culture; striatum; LGE; progenitor; precursor; radial glia; region specific; development; CNS; mouse; human; neurophysiology; Neurologi; neuropsykologi;

    Sammanfattning : The current thesis is aimed to increase our understanding of the generation and differentiation of telencephalic neurons, with emphasis on the role of glial cells in these processes. Using in vitro methods we have studied the role of glial cells in neurogenesis, inheritance of genetic regional specification, and influence on differentiation of neurons. LÄS MER

  7. 25. Bead based protein profiling in blood

    Författare :Maja Neiman; Peter Nilsson; Jochen Schwenk; Anja Persson; Heng Zhu; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Affinity proteomics; protein array; suspension bead array; antigen; antibody; biomarker discovery; serology; selectivity; sensitivity; serum; plasma;

    Sammanfattning : This thesis is about protein profiling in blood-derived samples using suspension bead ar- rays built with protein affinity reagents, and the evaluation of binding characteristics and potential disease relation of such profiles.A central aim of the presented work was to discover and verify disease associated protein profiles in blood-derived samples such as serum or plasma. LÄS MER