Sökning: "suspension bead array"
Visar resultat 1 - 5 av 17 avhandlingar innehållade orden suspension bead array.
1. Array-based identification of disease-associated proteins
Sammanfattning : To increase our understanding of the human body in both health and disease, proteins can be studied in samples such as plasma and serum to provide a molecular profile of the physiological status. In the work presented in this thesis, array-based methods were used to study associations of protein and autoantibody profiles with disease. LÄS MER
2. Bead based protein profiling in blood
Sammanfattning : This thesis is about protein profiling in blood-derived samples using suspension bead ar- rays built with protein affinity reagents, and the evaluation of binding characteristics and potential disease relation of such profiles.A central aim of the presented work was to discover and verify disease associated protein profiles in blood-derived samples such as serum or plasma. LÄS MER
3. Characterization of antibody specificity using peptide array technologies
Sammanfattning : Antibodies play an important role in the natural immune response to invading pathogens. The strong and specific binding to their antigens also make them indispensable tools for research, diagnostics and therapy. LÄS MER
4. Proteomic strategies for blood biomarker development in rare dystrophinopathies
Sammanfattning : Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are two rare genetic disorders of the family dystrophinopathy. They are both caused by the lack of, or reduced production of, the protein dystrophin. LÄS MER
5. Dementia Proteomics
Sammanfattning : The term dementia encompass a number of conditions arising as a consequence of tissue degeneration in the brain. This degeneration is caused by molecular events occurring on a cellular level including inflammation, defective waste disposal and accumulation of insoluble proteins and peptides. LÄS MER