Sökning: "PAP"

Visar resultat 1 - 5 av 76 avhandlingar innehållade ordet PAP.

  1. 1. Regulation of Mammalian Poly(A) Polymerase Activity

    Författare :Ann-Charlotte Thuresson; Barklie Clements; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicine; poly A polymerase; PAP; polyadenylation; isoforms; phosphorylation; alternative splicing; CPSF interaction; aminoglycosides; Biomedicin; Microbiology; Mikrobiologi; Molekylär cellbiologi; Molecular Cellbiology;

    Sammanfattning : Poly(A) polymerase (PAP) is the enzyme catalyzing the synthesis of the adenine tail to the 3’-end of mRNA. This A-tail is present on the majority of the primary RNA transcripts of protein-coding genes, and is important for mRNA stability, export to the cytoplasm and translation. Therefore, PAP is a key regulator of eukaryotic gene expression. LÄS MER

  2. 2. Physical activity as a treatment in primary health care. The role of the GP and Somali women’s views and levels of physical activity

    Författare :Gerthi Persson; Allmänmedicin och samhällsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physical activity; primary health care; PAP; accelerometer; physiotherapy;

    Sammanfattning : Physical inactivity has been identified as the fourth leading risk factor for global mortality and healthcare systems play a major role in increasing physical activity among the population. Physical activity on prescription (PAP) is a non-pharmacological method used in Swedish healthcare to prevent and treat disease. LÄS MER

  3. 3. Functional Significance of Multiple Poly(A) Polymerases (PAPs)

    Författare :Helena Nordvarg; Claire Moore; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; poly A polymerase; PAP; phosphorylation; isoforms; alternative splicing; kinetic parameters; hyperphosphorylation; regulation; Genetik; Poly A polymeras; PAP; fosforylering; isoformer; alternativ splitsning; kinetiska parametrar; reglering; Clinical genetics; Klinisk genetik; molekylär cellbiologi; Molecular Cellbiology;

    Sammanfattning : 3’ end cleavage and polyadenylation are important steps in the maturation of eukaryotic mRNAs. Poly(A) polymerase (PAP), the enzyme catalysing the addition of adenosine residues, exists in multiple isoforms. In this study the functional significance of multiple poly(A) polymerases have been investigated. LÄS MER

  4. 4. Estimating children’s exposure to per- and polyfluoroalkyl substances

    Författare :Kerstin Winkens; Ian T. Cousins; Urs Berger; Robin Vestergren; Heather M. Stapleton; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PFAS; PFAA; fluorinated; fluorotelomer; FTOH; PAP; early life; child; human; exposure; intake; indoor; bedroom; air; dust; serum; Applied Environmental Science; tillämpad miljövetenskap;

    Sammanfattning : Per- and polyfluoroalkyl substances (PFASs) are highly stable, surface active chemicals, which are water- and oil/stain-repellent. Because of their unique properties, PFASs are widely used in consumer products. LÄS MER

  5. 5. Women receiving notification of an abnormal Pap smear result : experiences and impact on health-related quality of life

    Författare :Marie Rask; Marie Oscarsson; Katarina Swahnberg; Karin Blomberg; Linnéuniversitetet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Abnormal Pap smear; human papillomavirus; cervical cancer screening; health-related qualtiy of life; anxiety; depression; HADS; FACIT-CD; translation; Vårdvetenskap; Caring Science;

    Sammanfattning : Aim: The aim of this thesis was to investigate experiences of receiving notification of an abnormal Pap smear result and its impact on women’s health-related quality of life as well as to investigate women’s awareness of human papillomavirus.Methods: In total, 176 women and 20 healthcare professionals participated. LÄS MER