Sökning: "injury mechanism"

Visar resultat 1 - 5 av 192 avhandlingar innehållade orden injury mechanism.

  1. 1. Head Injuries in Car-to-Pedestrian Accidents - Investigation of Head Impact Dynamics, Injury Mechanisms and Countermeasures

    Författare :Jianfeng Yao; [2010]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; accident analysis; head injury; head protection; mathematical simulation; accident reconstruction; injury mechanism; Pedestrian accident;

    Sammanfattning : The aim of this study was to investigate head impact dynamics and to establish risk functions for head injuries by mathematical reconstructions of real-world car-to-pedestrian accidents. Furthermore, an attempt was made to develop an approach for the design and evaluation of head-protective devices. LÄS MER

  2. 2. Injury-Induced Signalling in Arterial Smooth Muscle Cells

    Detta är en avhandling från Sara Moses, Lund University, Dept. Cell and Molecular Biology, BMC C12, 221 84 Lund

    Författare :Sara Moses; [2002]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GAG; Clinical biology; Klinisk biologi; proteoglycan; osteopontin; ERK; MAPK; signalling; smooth muscle cell; injury;

    Sammanfattning : The vascular wall is an active, elastic and integrated organ made up of cellular and extracellular matrix (ECM) components. It is not a static organ; the components dynamically change and reorganize in response to physiological and pathological stimuli. Vascular injury induces a complex healing process, analogous to generalised wound healing. LÄS MER

  3. 3. Definition of axonal injury tolerances across scales A computational multiscale approach

    Detta är en avhandling från Kungliga Tekniska högskolan

    Författare :Annaclaudia Montanino; Svein Kleiven; Alessandra Villa; Xiaogai Li; Kacy Cullen; [2020]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Traumatic Brain Injury; Axonal Injury; Mechanoporation; Multiscale;

    Sammanfattning : Traumatic brain injury (TBI) is today regarded as a global health challenge. Revealing how external mechanical loads translate into tissue and cellular damage is necessary, not only for the development of better preventive measures, but also for the definition of treatments that could spare the patients from suffering TBI's devastating consequences. LÄS MER

  4. 4. Pulmonary Injury Following Intestinal Ischemia and Reperfusion in Rats

    Detta är en avhandling från Department of Surgery, Clinical Sciences Lund, Lund University

    Författare :Anna Börjesson; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reperfusion injury; intestinal ischemia; pulmonary injury; endothelium; cytokines; alveolar fluid clearance; leukocytes; orthopaedics; Surgery; traumatology; ortopedi; Kirurgi; traumatologi;

    Sammanfattning : Intestinal ischemia and reperfusion (I/R) is a potentially life-threatening condition, sometimes leading to a systemic inflammatory response and the potential development of the multiple organ dysfunction syndrome. The overall aim of the thesis was to study the effects of intestinal I/R on pulmonary function with special emphasis on removal of excess alveolar fluid, pulmonary endothelial barrier permeability, leukocyte accumulation and function, and possible therapeutic strategies to prevent the development of pulmonary injury following intestinal I/R. LÄS MER

  5. 5. The inflammatory response to arterial injury

    Detta är en avhandling från Exp. Kardiovask. Forsk., Wallenberg Lab. Ingång 46 Plan 1 UMAS 205 02 Malmö

    Författare :Paul Dimayuga; [2001]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiovascular system; neointima; arterial injury; inflammation; Kardiovaskulära systemet;

    Sammanfattning : Atherosclerosis as a disease is postulated to stem from a response to injury of the arterial wall by various stimuli. The inflammatory response is proposed to mediate intimal formation after injury. One pathway of cellular response to injury is through transcription factor NF-kB. LÄS MER