Sökning: "injury mechanism"

Visar resultat 1 - 5 av 189 avhandlingar innehållade orden injury mechanism.

  1. 1. Stochastic finite element simulations of real life frontal crashes : With emphasis on chest injury mechanisms in near-side oblique loading conditions

    Författare :Johan Iraeus; Mats Lindquist; Ulf Björnstig; Mats G Larsson; Joel Stitzel; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; EDR; Real life crashes; Oblique; Finite element; Simulation; HBM; Injury mechanism; Pulse shape; Stochastic; Rib fracture; THUMS; Generic; Statistics; biomechanics; biomekanik; skadeförebyggande; injury prevention;

    Sammanfattning : Introduction. Road traffic injuries are the eighth leading cause of death globally and the leading cause of death among young people aged 15-29. Of individuals killed or injured in road traffic injuries, a large group comprises occupants sustaining a thorax injury in frontal crashes. The elderly are particularly at risk, as they are more fragile. LÄS MER

  2. 2. Head Injuries in Car-to-Pedestrian Accidents - Investigation of Head Impact Dynamics, Injury Mechanisms and Countermeasures

    Författare :Jianfeng Yao; Chalmers University of Technology; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; accident analysis; head injury; head protection; mathematical simulation; accident reconstruction; injury mechanism; Pedestrian accident;

    Sammanfattning : The aim of this study was to investigate head impact dynamics and to establish risk functions for head injuries by mathematical reconstructions of real-world car-to-pedestrian accidents. Furthermore, an attempt was made to develop an approach for the design and evaluation of head-protective devices. LÄS MER

  3. 3. Injury-Induced Signalling in Arterial Smooth Muscle Cells

    Författare :Sara Moses; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GAG; Clinical biology; Klinisk biologi; proteoglycan; osteopontin; ERK; MAPK; signalling; smooth muscle cell; injury;

    Sammanfattning : The vascular wall is an active, elastic and integrated organ made up of cellular and extracellular matrix (ECM) components. It is not a static organ; the components dynamically change and reorganize in response to physiological and pathological stimuli. Vascular injury induces a complex healing process, analogous to generalised wound healing. LÄS MER

  4. 4. Definition of axonal injury tolerances across scales : A computational multiscale approach

    Författare :Annaclaudia Montanino; Svein Kleiven; Alessandra Villa; Xiaogai Li; Kacy Cullen; KTH; []
    Nyckelord :ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Traumatic Brain Injury; Axonal Injury; Mechanoporation; Multiscale;

    Sammanfattning : Traumatic brain injury (TBI) is today regarded as a global health challenge. Revealing how external mechanical loads translate into tissue and cellular damage is necessary, not only for the development of better preventive measures, but also for the definition of treatments that could spare the patients from suffering TBI's devastating consequences. LÄS MER

  5. 5. Pulmonary Injury Following Intestinal Ischemia and Reperfusion in Rats

    Författare :Anna Börjesson; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reperfusion injury; intestinal ischemia; pulmonary injury; endothelium; cytokines; alveolar fluid clearance; leukocytes; orthopaedics; Surgery; traumatology; ortopedi; Kirurgi; traumatologi;

    Sammanfattning : Intestinal ischemia and reperfusion (I/R) is a potentially life-threatening condition, sometimes leading to a systemic inflammatory response and the potential development of the multiple organ dysfunction syndrome. The overall aim of the thesis was to study the effects of intestinal I/R on pulmonary function with special emphasis on removal of excess alveolar fluid, pulmonary endothelial barrier permeability, leukocyte accumulation and function, and possible therapeutic strategies to prevent the development of pulmonary injury following intestinal I/R. LÄS MER