Sökning: "RAG-1"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet RAG-1.

  1. 1. Human intraepithelial lymphocytes : a comparative study of phenotype, morphology, and functional properties of intraepithelial lymphocytes in gut and oral mucosa

    Författare :Carina Lundqvist; Marie-Louise Hammarström; Sten Hammarström; Per Brandtzaeg; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human intraepithelial lymphocytes; alimentary tract; intestinal epithelium; gut luminal antigens; gingiva; γδ T cells; immunoelectron microscopy; cytokine mRNA; RT-PCR; extrathymic T cell maturation; RAG-1; periodontitis; mucosal immune system; CD4-CD8- αβ T cells; CD8 γδ T cells;

    Sammanfattning : Human intraepithelial lymphocytes (IEL) constitute a unique cell population situated in the first line of defense of the alimentary tract. Here they are continuously exposed to a massive antigenic load of high complexity. However, different conditions prevail along the alimentary tract. LÄS MER

  3. 2. Clades in the "higher land bird assemblage"

    Författare :Ulf. S. Johansson; Scott V. Eswards; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Birds; Fåglar; Systematic Zoology; zoologisk systematik och evolutionsforskning;

    Sammanfattning : This thesis summarizes the results of several phylogenetic studies of birds included in the “higher land bird assemblage” (Anomalogonatae sensu Beddard 1898). The phylogenetic analyses are primarily based on gene sequences obtained from the nuclear genome (exons of the c-myc and RAG-1 genes and an intron of the myoglobin gene). LÄS MER

  4. 3. Functional collaboration between HLH transcription factors in B cell development

    Författare :Ramiro Gisler; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; E47; Early B cell Factor EBF ; Clinical genetics; Klinisk genetik; HLH proteins; transcription factors; gene expression; B cell development; transcription regulation;

    Sammanfattning : The cells in B cell development can be divided into several subgroups or fractions, e.g. early-pro-B-, pro-B, large-pre-B-, small-pre-B-, immature and mature B cells, where the stages reflect the maturity degree of the cells. LÄS MER

  5. 4. The inflammatory response to arterial injury

    Författare :Paul Dimayuga; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiovascular system; neointima; arterial injury; inflammation; Kardiovaskulära systemet;

    Sammanfattning : Atherosclerosis as a disease is postulated to stem from a response to injury of the arterial wall by various stimuli. The inflammatory response is proposed to mediate intimal formation after injury. One pathway of cellular response to injury is through transcription factor NF-kB. LÄS MER

  7. 5. Interferons in immunity to chlamydia pneumoniae

    Författare :Antonio Carlos Gigliotti (Tony) Rothfuchs; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Chlamydia pneumoniae; TLR; IFN-alpha beta; IFN-gamma; macrophages; T cells;

    Sammanfattning : The cytokine IFN-gamma is the architect behind an amazing immunological program of host resistance to intracellular bacterial and protozoan infections. IFN-gamma activates macrophages, making them into inhospitable habitats for parasites attempting to grow inside them. LÄS MER