Sökning: "alimentary tract"
Visar resultat 1 - 5 av 12 avhandlingar innehållade orden alimentary tract.
1. Human intraepithelial lymphocytes : a comparative study of phenotype, morphology, and functional properties of intraepithelial lymphocytes in gut and oral mucosa
Sammanfattning : Human intraepithelial lymphocytes (IEL) constitute a unique cell population situated in the first line of defense of the alimentary tract. Here they are continuously exposed to a massive antigenic load of high complexity. However, different conditions prevail along the alimentary tract. LÄS MER
2. Extrathymic T cell receptor gene rearrangement in human alimentary tract
Sammanfattning : T lymphocytes regulate the initiation, duration, and magnitude of adaptive immune responses and function as effector cells in cell mediated immunity. To become immunologically competent they must generate functional antigen receptors. This process takes place in the thymus and requires somatic recombination of T cell receptor (TCR) genes. LÄS MER
3. Microbiota of the alimentary tract of children - implications for allergy and inflammatory bowel disease
Sammanfattning : Allergy, which is the most common chronic disease in Swedish children and adolescents, is associated with a high standard of living and Western lifestyle. According to the hygiene hypothesis, allergy is due to inadequate stimulation of the immune system by microbes during early childhood, leading to failed maturation of the immune system. LÄS MER
4. Microbial regulation of PPARgamma : nuclear receptor networks important for colonic homeostasis
Sammanfattning : One of the central issues surrounding the physiology of good health is to uncover and understand the molecular networks responsible for its maintenance. The alimentary tract in particular, demands a properly sustained homeostatic control since it is constantly challenged by potentially harmful agents along with innocuous nutrients, with the burden of basic metabolic functions in its ward. LÄS MER
5. Signalling and activation of TLR4 by Gram-negative bacteria in epithelial cells
Sammanfattning : Lipopolysaccharide (LPS) is a well-characterized pathogen-associated molecule found primarily as a constituent of the outer membrane of Gram-negative bacteria. LPS is known to act on different cell types in a pleiotropic manner. LÄS MER