Sökning: "HIV DNA PCR"

Visar resultat 1 - 5 av 33 avhandlingar innehållade orden HIV DNA PCR.

  1. 1. On HIV-1 latency and viral reservoirs

    Författare :Tomas Mellberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; Latency; Intravenous immunoglobulin; residual viremia; low level viremia; Ultrasensitive PCR methods; Central nervous system;

    Sammanfattning : HIV-1 establishes a latent infection that is inaccessible to treatment in cellular and anatomical reservoirs. This thesis concerns several problematic issues of HIV-1 persistence, including ways to measure and monitor both the virus at low viral concentrations and the depletion of the reservoir. LÄS MER

  3. 2. Studies on genital ulcer disease in Tanzania. Aetiology with special reference to Haemophilus ducreyi, association with human immunodeficiecy virus infection, and human papilloma virus

    Författare :Judica Mbwana; Göteborgs universitet; []
    Nyckelord :GUD; H. ducreyi; HSV-2; HIV-1; HdCDT; ELISA; RAPD; PCR; HPV;

    Sammanfattning : Genital ulcer diseases (GUD) caused by Haemophilus ducreyi, Treponema pallidum and herpessimplex type 2 (HSV-2) are an important health problem in many developing countries. Ulcerativesexually transmitted infections (STIs) have been associated with increased acquisition andtransmission of human immunodeficiency virus type 1 (HIV-1). LÄS MER

  4. 3. HIV therapies : from health-related quality of life to DNA levels

    Författare :Lars E Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :AIDS; antiretroviral therapy; CD4; DNA load; HIV; immunotherapy; viral kinetics; nursing; medical care; quality of life; real-time PCR; rgpl60; RNA load; therapy interruption.;

    Sammanfattning : The treatment of people infected with HIV was revolutionised with the introduction of protease inhibitor based antiretroviral combination therapy. The therapy has greatly reduced the incidence of AIDS and AIDS-related mortality in the industrialised world. LÄS MER

  5. 4. Reverse Transcriptase Activity Assays for Retrovirus Quantitation and Characterization

    Författare :Anders Malmsten; Ulf Gyllensten; Clas Källander; Lynn Morris; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; retrovirus; reverse transcriptase; enzyme activity assay; MuLV; HIV; RT purification; viral load; drug susceptibility; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Sammanfattning : Reverse transcriptase (RT) is a crucial enzyme for retrovirus replication, and its presence in the virion is indispensable for infectivity. This thesis illustrates the use of RT activity assays as tools for quantitation and characterization of different retroviruses, particularly HIV. LÄS MER

  7. 5. Regulation of HIV-1 provirus transcription

    Författare :Mojgan H Naghavi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Key words- HIV-1; LTR; transcription; subtypes; phylogenetic analysis; NFkappaB; USF; MCEF; HMG-1 DSP1; Dorsal.;

    Sammanfattning : Transcription of the HIV-genome is regulated by the interaction of viral long terminal repeat (LTR) cis-acting sequences with a complex of viral regulatory proteins and cellular transcription factors. The complex interplay between the cellular-, and/or viral proteins and LTR of different subtypes may play a role in the control of HIV-1 latency versus activation. LÄS MER