Sökning: "drug susceptibility"
Visar resultat 1 - 5 av 118 avhandlingar innehållade orden drug susceptibility.
1. Studies of Retroviral Reverse Transcriptase and Flaviviral Protease Enzymes as Antiviral Drug Targets : Applications in Antiviral Drug Discovery & Therapy
Sammanfattning : Viruses are a major threat to humans due to their unique adaptability, evolvability and capability to control their hosts as parasites and genetic elements. HIV/AIDS is the third largest cause of death by infectious diseases in the world, and drug resistance due to the viral mutations is still the leading cause of treatment failure. LÄS MER
2. Tuberculosis : diagnosis and drug susceptibility testing where resources are scarce
Sammanfattning : Background: Tuberculosis remains a major global public health problem. Not surprisingly, most cases of this disease occur in poor countries and an increasing number of patients harbor drug - resistant bacteria. The cornerstone of bacteriological diagnosis of tuberculosis is direct sputum smear microscopy. LÄS MER
3. Water-swelling tablets based on hydrophobically modified poly(acrylic acid) - Effects of amphiphiles on swelling and drug release
Sammanfattning : An important issue within the pharmaceutical world today is the increasing number of poorly soluble drugs. These often show a low bioavailability and a susceptibility to varying conditions in the intestine. LÄS MER
4. Reverse Transcriptase Activity Assays for Retrovirus Quantitation and Characterization
Sammanfattning : Reverse transcriptase (RT) is a crucial enzyme for retrovirus replication, and its presence in the virion is indispensable for infectivity. This thesis illustrates the use of RT activity assays as tools for quantitation and characterization of different retroviruses, particularly HIV. LÄS MER
5. Drug resistance in mycobacterium tuberculosis
Sammanfattning : Drug-resistant tuberculosis is a global public health problem. This investigation was performed to find ways of improving regimens that could be used for the treatment of drug- and multidrug-resistant TB and also to find a rapid method of diagnosis of drug resistant TB, particularly MDR-TB. Among 107 isolates of M. LÄS MER