Visar resultat 1 - 5 av 422 avhandlingar innehållade ordet ELISA.
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Sammanfattning : Population ageing means that increasingly many are faced with the dual demands of paid work while providing unpaid care to older family members. Caregiving requires time and energy, with implications for paid work and well-being. The challenges faced by individuals add up and therefore also impact national economies. LÄS MER
3. A frizzled quest to dissect the molecular pharmacology of WNT signaling : from biology to signaling mechanism(s)
Sammanfattning : The wingless/int1 (WNT)/Frizzled (FZD) family of signal transduction pathways is highly conserved across species and controls essential physiological functions important for embryonic development, stem cell renewal, proliferation, differentiation, and cell polarity. Dysregulation of these signaling pathways leads to developmental abnormalities or other conditions such as inflammation, cancer, or neurological disorders. LÄS MER
Sammanfattning : Where do babies come from? Even though it sounds like a fairly obvious question, it took more than 200 years to discover that sperm, whose first observation dates back to the 17th century, can penetrate into the oocyte and fuse with it. Interestingly, this initial study was carried out in starfish, and since then, scientists have addressed the fascinating question of how gamete recognition functions using very different model systems. LÄS MER
5. Amyotrophic lateral sclerosis and multiple sclerosis associated neuroinflammation : nationwide epidemiological studies on etiology, comorbidities, and treatment
Sammanfattning : Amyotrophic lateral sclerosis (ALS) is a relatively rare but fatal neurodegenerative disease characterized by progressive muscle paralysis, due to loss of upper and lower motor neurons. Signs of neuroinflammation have been reported in ALS, however it is still unknown whether neuroinflammation is a cause or a consequence of the motor neuron dysfunction. LÄS MER