Sökning: "low level viremia"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden low level viremia.

  1. 1. Low-level HIV viremia during antiretroviral therapy

    Författare :Olof Elvstam; Klinisk infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human immunodeficiency virus; Viral load; Antiretroviral therapy; Mortality; Malignancies; Cardiovascular disease;

    Sammanfattning : In most cases, antiretroviral therapy (ART) results in undetectable plasma HIV viral load (VL). Still, up to 25% of ART recipients may have detectable low-level viremia (LLV) of different amplitude and persistence. This thesis explores the impact of LLV during ART on virologic and clinical outcomes. LÄS MER

  3. 2. On HIV-1 latency and viral reservoirs

    Författare :Tomas Mellberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; Latency; Intravenous immunoglobulin; residual viremia; low level viremia; Ultrasensitive PCR methods; Central nervous system;

    Sammanfattning : HIV-1 establishes a latent infection that is inaccessible to treatment in cellular and anatomical reservoirs. This thesis concerns several problematic issues of HIV-1 persistence, including ways to measure and monitor both the virus at low viral concentrations and the depletion of the reservoir. LÄS MER

  4. 3. Chronic hepatitis B in children

    Författare :Ann Söderström; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Chronic hepatitis B affects more than 350 million people. In areas of high and intermediate endemicity, hepatitis B virus (HBV) infection is mainly contracted in the perinatal period or early childhood, and many of them become chronic carriers. LÄS MER

  5. 4. Very preterm birth : etiological aspects and short and long term outcomes

    Författare :Stefan Johansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Very preterm birth, occurring before 32 completed weeks of gestation, is an often unexplained pregnancy complication affecting approximately 1 to 2 percent of all births. This thesis includes four studies regarding the etiology, and short and long term outcomes of very preterm birth, using Swedish population-based data. LÄS MER

  7. 5. Alphavirus vectors as recombinant vaccines

    Författare :Peter Berglund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Semliki Forest virus; Alphavirus; Synthetic vaccmes; Influenza A virus; HIV-I; SIV; DNA vaccines; AIDS vaccines; Influenza vaccine;

    Sammanfattning : This thesis describes further developments of an expression system based on the alphavirus Semliki Forest virus (SFV), and its potential use as recombinant vaccine. The RNA genome of SFV contains a 3'open reading frame (ORF) encoding the structural proteins, and a 5' ORF coding for the viral replicase. LÄS MER