Sökning: "Ulf Gyllensten"
Visar resultat 1 - 5 av 23 avhandlingar innehållade orden Ulf Gyllensten.
1. Biochemical genetic variation, intraspecific genetic structure and postglacial evolution of select north European vertebrate species
Sammanfattning : Analysis of the tempo and mode of intraspecific differentiation provides important information for understanding subspeciation, for construction of taxonomic hierarchies within a species and for management of genetic variation in natural populations.The present thesis describes the genetic structure of natural populations of willow grouse (Lagopus tagopus L. LÄS MER
2. Self-sampling for HPV testing in primary cervical screening : Including clinical and health economic aspects
Sammanfattning : Persistent infection with high-risk human papillomavirus (HPV) is a prerequisite for the development of cervical cancer. HPV testing has higher sensitivity for high-grade cervical intraepithelial neoplasia (CIN2+) than cytology, resulting in more effective screening. LÄS MER
3. Sensitive Forensic DNA Analysis : Application of Pyrosequencing and Real-time PCR Quantification
Sammanfattning : The field of forensic genetics is growing fast and the development and optimisation of more sensitive, faster and more discriminating forensic DNA analysis methods is highly important. In this thesis, an evaluation of the use of novel DNA technologies and the development of specific applications for use in forensic casework investigations are presented. LÄS MER
4. Identification and clinical implementation of biomarkers for cervical cancer
Sammanfattning : Introduction of organised screening programs and prophylactic vaccination against human papilloma virus (HPV) have successfully reduced the incidence of cervical cancer globally. In Sweden, the incidence has been reduced by about 50 % since the introduction of the national screening programme in the late 1960’s. LÄS MER
5. Dissecting the Genetic Basis of Systemic Lupus Erythematosus : The Pursuit of Functional Variants
Sammanfattning : Systemic lupus erythematosus (SLE) is a chronic and systemic autoimmune disease that primarily affects women during the childbearing years. SLE is characterized by the production of autoantibodies against nucleic acids and their interacting proteins. LÄS MER