Sökning: "AMPs"

Visar resultat 26 - 30 av 57 avhandlingar innehållade ordet AMPs.

  1. 26. Modeling aerosol-cloud interactions in the Arctic

    Författare :Hannah Frostenberg; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mixed-phase clouds; ice nucleating particles; heterogeneous freezing; Arctic; LES-modeling; parameterization;

    Sammanfattning : Clouds have a large impact on Earth’s energy balance, especially in the Arctic. Through their warming or cooling effect on the surface, clouds can play a critical role in the onset of melting and freezing of Arctic sea ice, which itself has a large effect on energy and moisture fluxes between the ocean and the atmosphere. LÄS MER

  3. 27. Severe Head Injury. Evaluation of Acute Treatment and Rehabilitation

    Författare :Christer Eker; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurologi; neuropsykologi; neurofysiologi; cerebral blood flow; neuropsychological test; assessment of motor and process skills; rehabilitation; Neurology; neuropsychology; neurophysiology; intracranial pressure; Severe head injury; intensive care;

    Sammanfattning : Mortality after severe head injury can be considerably reduce with a therapy using physiological principles for brain volume regulation and preserved microcirculation, with the main purpose of restricting the rise in ICP to reasonable levels simultaneously with preservation of adequate blood supply. This study shows that the ?Lund Concept? can reduce mortality in patients with severe traumatic brain lesions from 47% to 8%. LÄS MER

  4. 28. Antimicrobial peptides and virulence factors in meningococcal colonisation and disease

    Författare :Miriam Geörg; Ann-Beth Jonsson; Ole E. Sørensen; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Neisseria meningitidis; antimicrobial peptide; LL-37; cell-penetrating peptide; resistance; polynucleotide phosphorylase; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : The Gram-negative bacterium Neisseria meningitidis is a transient commensal of the human nasopharynx, but occasionally causes life-threatening disease. During colonisation of its niche, N. meningitidis has to overcome innate immune defences, including the expression of antimicrobial peptides (AMPs). LÄS MER

  5. 29. Regulation of antimicrobial peptide gene expression in Drosophila melanogaster : Involvement of POU and NF-kB/Rel factors in innate immunity

    Författare :Anna Junell; Ylva Engström; Jean-Luc Imler; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : The fruit fly, Drosophila melanogaster, has a well-developed immune response, and microbial assault induces a rapid production of potent antimicrobial peptides (AMPs). The aim of this thesis work was to gain deeper knowledge of the regulation of AMPs in Drosophila, by the isolation and characterization of transcription factors involved in AMP gene expression. LÄS MER

  7. 30. Bacterial Resistance to Antimicrobial Peptides : Rates, Mechanisms and Fitness Effects

    Författare :Maria Pränting; Dan Andersson; Ian Chopra; Uppsala universitet; []
    Nyckelord :antimicrobial peptides; antibiotic resistance; fitness cost; bacterial evolution; small colony variants; cyclotides; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology; Mikrobiologi; Microbiology;

    Sammanfattning : The rapid emergence of bacterial resistance to antibiotics has necessitated the development of alternative treatment strategies. Antimicrobial peptides (AMPs) are important immune system components that kill microbes rapidly and have broad activity-spectra, making them promising leads for new pharmaceuticals. LÄS MER