Sökning: "AMPs"

Visar resultat 36 - 40 av 57 avhandlingar innehållade ordet AMPs.

  1. 36. Endotoxin-induced inflammation in healthy human airways

    Författare :Margaretha E. Smith; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LPS; neutrophils; bronchoalveolar lavage; human airways; innate immunity;

    Sammanfattning : The aim of this thesis was to investigate the innate immune response in healthy human airways in vivo after simulation of a Gram-negative infection. Intrabronchial exposure to the TLR4 agonist endotoxin was used as a model for the innate mechanisms in the immune response that are caused by cigarette smoke and by natural infection with Gram-negative bacteria. LÄS MER

  3. 37. The Fight on the Flights : Emergency evacuations – human physiological performance, leg muscle activity and gait biomechanics during exhaustive stair and slope ascent

    Författare :Amitava Halder; Ergonomi och aerosolteknologi; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Stair climbing evacuation; Physical work capacity; Physiological constraints; Endurance; Energy expenditure; Oxygen consumption; Electromyography; Muscle fatigue; Incline gait biomechanics; Ground reaction forces; Required coefficient of friction;

    Sammanfattning : Physical exhaustion can constrain stair ascending capacity during emergency evacuation. The overall aim of this research was to explore and compare stair ascending capacities and physiological limitations when using two different modes: 1) self-preferred pace on three different public stairways, and 2) four machine-controlled paces on a stair machine corresponding to different percentages of maximal aerobic capacity (V̇O2max). LÄS MER

  4. 38. Signaling and transcriptional regulation of antimicrobial peptide genes in Drosophila melanogaster

    Författare :Hanna Uvell; Ylva Engström; Won-Jae Lee; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; antimicrobial peptides; drosophila; immunity; transcriptiona regulation; Molecular biology; Molekylärbiologi;

    Sammanfattning : Insects rely solely on innate immune reactions for protection against infect-ing microbes in their environment. In Drosophila, one major defense mechanism is the production of a battery of antimicrobial peptides (AMPs). LÄS MER

  5. 39. HIV susceptibility factors in the human genital mucosa

    Författare :Maria Röhl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Heterosexual HIV transmission is the most common viral transmission route worldwide. To establish a persistent infection the virus needs to cross the mucosal surface of the genital tract. The genital mucosa is thus considered to be the portal of HIV entry and initial site of viral replication. LÄS MER

  7. 40. Grainy head target genes in epithelial morphogenesis and wound healing

    Författare :Shenqiu Wang; Christos Samakovlis; Paul Martin; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; grh; targets; epidermal wound repair; tracheal tube size control; local immune responses; stit; verm; serp; PGRP-LC; CecA-LacZ; Developmental biology; Utvecklingsbiologi; utvecklingsbiologi; Developmental Biology;

    Sammanfattning : grainy head (grh) genes encode a family of transcription factors conserved from fly to human. Drosophila grh is the founding member of this gene family and has multiple functions, including tracheal tube size control, epidermal barrier formation and reconstruction after wounding. LÄS MER