Sökning: "Perfusion medium optimization"

Hittade 2 avhandlingar innehållade orden Perfusion medium optimization.

  1. 1. Tools for the development of intensified perfusion processes for mammalian cell culture

    Författare :Hubert Schwarz; Véronique Chotteau; Mark Smales; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Recombinant protein biomanufacturing; Perfusion process; Integrated continuous bioprocessing; Monoclonal antibody; Erythropoietin; Chinese Hamster Ovary cells; Human Embryonic Kidney cells; Perfusion medium optimization; Cell specific perfusion rate; Raman spectroscopy; N-glycosylation; Microbioreactors; Design of Experiments; Biotechnology; Bioteknologi;

    Sammanfattning : Recombinant protein therapeutics have become an indispensable part of modern medicine to treat a wide variety of diseases. Their manufacture is mostly based on mammalian cells with fed-batch production bioreactors and downstream batch purification unit operations. LÄS MER

  3. 2. Tissue engineering for novel female infertillity treatments: studies on small and large animal models

    Författare :Arvind M. Padma; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rat; sheep; tissue engineering; decellularization; recellularization;

    Sammanfattning : Introduction: As with any transplantation (Tx) procedure, uterus Tx is associated with risky donor surgery and adverse side-effects from immunosuppression. With the aim to bypass these risks, this thesis investigated uterus tissue engineering strategies and the potential to develop a patient-specific uterus graft to replace the need for donor surgery and immunosuppression. LÄS MER