Sökning: "uncoupling protein 1"

Visar resultat 1 - 5 av 33 avhandlingar innehållade orden uncoupling protein 1.

  1. 1. Uncoupling Proteins : Regulation by IGF-1 and Neuroprotection during Hyperglycemia in Vitro

    Författare :Helena Gustafsson; Anna Forsby; David Tomlinson; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; uncoupling protein; oxidative stress; diabetes; neuropathy; SH-SY5Y; Neurobiology; Neurobiologi;

    Sammanfattning : Diabetic neuropathy is believed to arise due to oxidative stress following hyperglycemic situations. Uncoupling proteins (UCPs) constitute a subgroup of mitochondrial transporter proteins with putative antioxidant properties. LÄS MER

  3. 2. Enterostatin - target proteins and intracellular mechanisms. Function in food intake and energy metabolism

    Författare :Karin Berger; Molekylär endokrinologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ATP; energy metabolism; insulin; uncoupling protein; beta-casomorphin; opiate; SK-N-MC; INS-1; Medicin människa och djur ; Medicine human and vertebrates ; fat intake; F1F0-ATP synthase; appetite; enterostatin; satiety; obesity;

    Sammanfattning : Hunger and satiety are the results of complex neural events that involve several neurotransmitters and peptides. Enterostatin is an appetite-regulating peptide released in the intestine in response to fat ingestion. Enterostatin specifically decreases fat intake, but has also metabolic effects like inhibition of insulin secretion. LÄS MER

  4. 3. Dietary, Pharmacological and Environmental Effects on Brown Adipose Tissue

    Författare :Erik Lindsund; Tore Bengtsson; Jan Nedergaard; Karsten Kristiansen; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Obesity; brown adipose tissue; uncoupling protein 1; moderate cold exposure; calorimetry; thyroxine; dietary protein; thermic effect of food; diet-induced thermogenesis; adrenergic stimulation; mice; physiology; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Obesity is a common health issue; over 12 % of the adult world population have obesity. Obesity has many co-morbidities including cardo-vascular diseases and diabetes. Obesity is the result of chronic positive energy balance, eating too much and expending too little. LÄS MER

  5. 4. Comparative analysis of the thermogenic protein UCP1 across the mammalian phylogeny

    Författare :Michael James Gaudry; Martin Jastroch; Tobias Wang; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Uncoupling protein 1; Evolution; Non-shivering thermogenesis; Brown adipose tissue; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Uncoupling protein 1 (UCP1) drives mitochondrial inefficiency to produce heat in mammalian brown adipose tissue (BAT). Many mammalian species rely on this form of adaptive non-shivering thermogenesis (NST) to defend high body temperatures in the cold. LÄS MER

  7. 5. On protein oxidation, lifespan and aging in Saccharomyces cerevisiae

    Författare :Hugo Aguilaniu; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; asymmetric cell division; protein oxidation; yeast; aging; signalling pathways;

    Sammanfattning : In this thesis, we have investigated the physiology of protein oxidation and its possible role in the aging of the yeast Saccharomyces cerevisiae. There are two ways to measure yeast aging. First, they can only divide a finite number of times even when all nutrients necessary for division are provided. This is replicative aging. LÄS MER